Overview

  • Product nameAnti-CCR11 antibody
    See all CCR11 primary antibodies
  • Description
    Goat polyclonal to CCR11
  • SpecificityPeptide sequence is < 50 % identical to other human chemokine receptors in this region. Please note there are two proteins called CCR11. This antibody is useful in identifying CCR11 and CCRL1 (not CCR11 and CCRL2).
  • Tested applicationsELISA, ICC, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:

    EQNQSTDYYYEENEMNGTYDYSQYELIC

    , corresponding to amino acids 4-31 of Human CCR11.

  • Positive control
    • Human heart, lung or small intestine.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPBS, 1mg/ml BSA, 0.1% sodium azide, pH7.2
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab1660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/75000.
ICC 1/500.
IHC-P 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Recommend to perform with Dako buffer S-1700, pH 6, steam for 20 min, cool for 20 min
WB 1/1000. Detects a band of approximately 45 kDa. CCR11 has 351 amino acids with 3 glycosylation sites and 7 hydrophobic domains. 7TMs generally run slower than other proteins of similar MW

Target

  • FunctionReceptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25.
  • Tissue specificityPredominantly expressed in heart. Lower expression in lung, pancreas, spleen, colon, skeletal muscle and small intestine.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C chemokine receptor type 11 antibody
    • C-C chemokine receptor type 11 antibody
    • C-C CKR-11 antibody
    • CC chemokine receptor like 1 antibody
    • CC chemokine receptor-like 1 antibody
    • CC CKR 11 antibody
    • CC-CKR-11 antibody
    • CCBP2 antibody
    • CCCKR11 antibody
    • CCR 11 antibody
    • CCR-11 antibody
    • CCR10 antibody
    • CCR11 antibody
    • CCRL1 antibody
    • CCRL1_HUMAN antibody
    • CCX CKR antibody
    • Chemocentryx chemokine receptor antibody
    • Chemokine (C C motif) receptor like 1 antibody
    • Chemokine cc motif receptor like protein 1 antibody
    • Chemokine receptor like 1 antibody
    • CKR11 antibody
    • CKRB antibody
    • Orphan seven transmembrane receptor chemokine related antibody
    • PPR1 antibody
    • Putative gustatory receptor type B antibody
    • VSHK1 antibody
    see all

Anti-CCR11 antibody images

  • Immunohistochemistry using ab1660 on human lung tissue section
  • Immunohistochemistry using ab1660 on human lung tissue section

References for Anti-CCR11 antibody (ab1660)

This product has been referenced in:
  • Zeng XH  et al. Absence of multiple atypical chemokine binders (ACBs) and the presence of VEGF and MMP-9 predict axillary lymph node metastasis in early breast carcinomas. Med Oncol 31:145 (2014). Read more (PubMed: 25097078) »
  • Feng LY  et al. Involvement of a novel chemokine decoy receptor CCX-CKR in breast cancer growth, metastasis and patient survival. Clin Cancer Res 15:2962-70 (2009). WB, IHC ; Human . Read more (PubMed: 19383822) »

See all 6 Publications for this product

Product Wall

The lab was very impressed by the level of information you provided and would like to help as much as possible. Their interpretation of the data sent is that the knock out mouse does not have deletion of the gene but a disruption of the coding sequ...

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Here is more information that I hope will be helpful. Q: In western blotting of wild type mice, a band is seen at 35kDa, is this CCR11? A: CCR11 has 351 amino acids with 3 glycosylation sites and 7 hydrophobic domains. 7TMs generally slower than...

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Following extensive research we have discovered that there are two proteins called CCR11(the nomenclature has a confusing history) and that this antibody should be identified as identifying CCR11 and CCRL1 and not CCR11 and CCRL2, I have made this clea...

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Thank you for your enquiry. You should see a band at approximately 40 kDa. If you have any further questions, please contact us again.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"