Overview
- Product nameAnti-CCR11 antibodySee all CCR11 primary antibodies ...
- DescriptionGoat polyclonal to CCR11
- SpecificityPeptide sequence is < 50 % identical to other human chemokine receptors in this region. Please note there are two proteins called CCR11. This antibody is useful in identifying CCR11 and CCRL1 (not CCR11 and CCRL2).
- Tested applicationsELISA, ICC, IHC-P, WB more details
- Species reactivityReacts with: Mouse, Human
- Immunogen
Synthetic peptide: EQNQSTDYYYEENEMNGTYDYSQYELIC, corresponding to amino acids 4-31 of Human CCR11.
- Positive controlHuman heart, lung or small intestine.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPBS, 1mg/ml BSA, 0.1% sodium azide, pH7.2
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Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab1660 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| ELISA | ELISA: 1/75000. |
| ICC | ICC: 1/500. |
| IHC-P | IHC-P: 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Recommend to perform with Dako buffer S-1700, pH 6, steam for 20 min, cool for 20 min |
| WB | WB: 1/1000. Detects a band of approximately 45 kDa. CCR11 has 351 amino acids with 3 glycosylation sites and 7 hydrophobic domains. 7TMs generally run slower than other proteins of similar MW |
Target
- FunctionReceptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25.
- Tissue specificityPredominantly expressed in heart. Lower expression in lung, pancreas, spleen, colon, skeletal muscle and small intestine.
- Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
- Cellular localizationCell membrane.
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Database links
- Entrez Gene: 51554 Human
- Entrez Gene: 51554 Human
- Entrez Gene: 252837 Mouse
- Omim: 606065 Human
- SwissProt: Q9NPB9 Human
- SwissProt: Q9NPB9 Human
- SwissProt: Q924I3 Mouse
- Unigene: 310512 Human
- Unigene: 729361 Human
- Unigene: 269254 Mouse
see all
Target information above from: UniProt accession
Q9NPB9
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- C C chemokine receptor type 11 antibodyC-C chemokine receptor type 11 antibodyC-C CKR-11 antibody
- CC chemokine receptor like 1 antibodyCC chemokine receptor-like 1 antibodyCC CKR 11 antibodyCC-CKR-11 antibodyCCBP2 antibodyCCCKR11 antibodyCCR 11 antibodyCCR-11 antibodyCCR10 antibodyCCR11 antibodyCCRL1 antibodyCCRL1_HUMAN antibodyCCX CKR antibodyChemocentryx chemokine receptor antibodyChemokine (C C motif) receptor like 1 antibodyChemokine cc motif receptor like protein 1 antibodyChemokine receptor like 1 antibodyCKR11 antibodyCKRB antibodyOrphan seven transmembrane receptor chemokine related antibodyPPR1 antibodyPutative gustatory receptor type B antibodyVSHK1 antibody
see all
Anti-CCR11 antibody images
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Immunohistochemistry using ab1660 on human lung tissue section
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Immunohistochemistry using ab1660 on human lung tissue section
Protocols
References for Anti-CCR11 antibody (ab1660)
This product has been referenced in:
- Feng LY et al. Involvement of a novel chemokine decoy receptor CCX-CKR in breast cancer growth, metastasis and patient survival. Clin Cancer Res 15:2962-70 (2009). WB, IHC ; Human . Read more (PubMed: 19383822) »
- Berencsi K et al. Colon carcinoma cells induce CXCL11-dependent migration of CXCR3-expressing cytotoxic T lymphocytes in organotypic culture. Cancer Immunol Immunother 56:359-70 (2007). Read more (PubMed: 16783574) »



