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- CCR2 antibody (ab19129)
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Product Name
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CCR2 antibody
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See all CCR2 antibodies (8)...
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Product type
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Primary antibodies
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Description
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Chicken polyclonal to CCR2
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Immunogen
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Recombinant fragment, corresponding to amino acids 1-45 of Human CCR2.
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Reacts with
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/1000. Predicted molecular weight: 43 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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E coli-derived fusion protein.
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Cellular localization
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Membrane; multi pass membrane protein.
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Research areas
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Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Leukocyte recruitment >> Chemokines
Cancer >> Signal transduction >> G protein signaling >> GPCR
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> STATs
Microbiology >> Interspecies Interaction >> Host Virus Interaction
Immunology >> Innate Immunity >> Chemokines >> Beta Chemokine Rec. (CCR)
Immunology >> Innate Immunity >> Macrophage / Inflamm.
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Relevance
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CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Chicken
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Clonality
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Polyclonal
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Isotype
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IgY
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Purity
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Protein L purified
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Storage buffer
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Preservative: None
Constituents: PBS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CCR2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CCR2 antibody images, references, products related to ab19129 and other tools.
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CCR2 antibody images:
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 - CCR2 antibody (ab19129)
Predicted band size : 43 kDa
ab19129 at 1/1000 staining E. coli-derived fusion protein by western blot. Detected using a goat anti-IgY-HRP and colorimetric method was used for signal development.
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Search PubMed (MEDLINE) for references to CCR2
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CCR2 antibody - more information
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Customer reviews (feedback) regarding CCR2 antibody |
Customer FAQs regarding CCR2 antibody |
Protocols for CCR2 antibody |
Price and availability of products related to CCR2 antibody |
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CCR2 antibody - related products:
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CCR2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about CCR2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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