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Products:Immunology >> Adaptive Immunity >> B Cells >> CD
Overview
Product name
Anti-CD10 antibody [MEM-78]
See all CD10 products (33) ...
Description
Mouse monoclonal [MEM-78] to CD10
Specificity
Human CD10 antigen (CALLA)
Tested applications
IP, Flow Cytmore details
Cross reactivity
Reacts with
Human
Immunogen
Tissue / cell preparation (Human). (Pre-B cell line NALM-6).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
>95% by SDS-PAGE
Purification notes
Purified from ascites using Protein A affinity chromatography.
Clonality
Monoclonal
Clone number
MEM-78
Isotype
IgG1
Research areas
Cancer >> Tumor immunology >> CD markers
Stem Cells >> Mesenchymal Stem Cells >> Surface Molecules
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Cell Type Markers >> CD >> Non-lineage
Immunology >> Adaptive Immunity >> B Cells >> CD
Applications
Show applications key
Our Abpromise guarantee covers the use of ab659 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: Use at an assay dependent concentration.
Flow Cyt: Use a concentration of 1 µg/ml
Target
Function
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Sequence similarities
Belongs to the peptidase M13 family.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionP08473
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Atriopeptidase antibody
- CALLA antibody
- CD 10 antibody
see all
Database links
- Entrez Gene: 4311 Human
- Omim: 120520 Human
- SwissProt: P08473 Human
- Unigene: 307734 Human
References for Anti-CD10 antibody [MEM-78] (ab659)
This product has been referenced in:
- Knapp W (eds.) et al. Leucocyte typing IV. Oxford University Press : (1989).Read more (PubMed: ) »
- Horejsi Vet al. Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74). Folia Biol (Praha) 34:23-34 (1988).Read more (PubMed: 2968928) »
See all 2 publications for this product
Publishing research using ab659? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"