Anti-CD105 antibody (ab21222)

Overview

• Product nameAnti-CD105 antibodySee all CD105 primary antibodies ...
• Description
  Rabbit polyclonal to CD105
• Tested applicationsELISA, WB more details
• Species reactivity
  Reacts with: Mouse
  
• Immunogen

  Highly pure recombinant mouse soluble CD105 (aas 26-581) bearing His 6 C-terminal tag.

Properties

• FormLyophilised:The lyophilized IgG is stable at 4°C for at least six months and for greater than a year when kept at –20°C. When reconstituted in sterile water/PBS to a concentration of >0.5 mg/ml the antibody is stable for at least six weeks at 2-4°C. Avoid repeated freeze-thaw cycles.
• Storage instructionsStore at +4°C. Aliquot and store at -20°C or -80°C when reconstituted. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS, pH 7.4
• Concentration information loading...
• PurityProtein A purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Stem Cells
  • Mesenchymal Stem Cells
  • Surface Molecules

  • Stem Cells
  • Endothelial Progenitors
  • Endothelial Markers

  • Cancer
  • Tumor biomarkers
  • Other

  • Cardiovascular
  • Vasculature
  • Endothelium

  • Cardiovascular
  • Cardiovascular Markers
  • Cell Markers
  • Endothelial Cells

  • Immunology
  • Cell Type Markers
  • CD
  • Endothelial Cells

Applications

Target

• FunctionMajor glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
• Tissue specificityEndoglin is restricted to endothelial cells in all tissues except bone marrow.
• Involvement in diseaseDefects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
• Cellular localizationMembrane.

Target information above from: UniProt accession P17813 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 13805 Mouse
  • SwissProt: Q63961 Mouse
  • Unigene: 225297 Mouse

• Alternative names
  CD 105 antibodyCD105 antibodyCD105 antigen antibody

  EGLN_HUMAN antibodyEND antibodyEndoglin antibodyENG antibodyFLJ41744 antibodyHHT1 antibodyORW antibodyORW1 antibodyOsler Rendu Weber syndrome 1 antibodyRP11 228B15.2 antibodySN6 antibody

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Anti-CD105 antibody images

• 

  Western blot - CD105 antibody (ab21222)
  All lanes : Anti-CD105 antibody (ab21222)
  
  Lane 1 : Recombinant mouse soluble CD105
  Lane 2 : Recombinant human soluble CD105
  
  
  Predicted band size : 71 kDa
  Observed band size : 71 kDa