![Flow Cytometry - CD11c antibody [N418] (Biotin) (ab95765) image](#CD11c-Primary-antibodies-ab95765-1.gif)
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Product name
Anti-CD11c antibody [N418] (Biotin)
See all CD11c products (21) ...
Description
Armenian Hamster monoclonal [N418] to CD11c (Biotin)
Conjugation
Biotin
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Mouse
Immunogen
Mouse spleen dendritic cells.
Positive control
C57BL/6 splenocytes.
Properties
Form
Liquid
Storage instructions
Store at +4°C. Do not freeze.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS, 150mM Sodium chloride, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
N418
Isotype
IgG
Research areas
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Dendritic Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Immunology >> Cell Type Markers >> CD >> Adhesion
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Alpha
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Flow Cytometry - CD11c antibody [N418] (Biotin) (ab95765)
![Flow Cytometry - CD11c antibody [N418] (Biotin) (ab95765) image](/ps/datasheet/images/95/ab95765/CD11c-Primary-antibodies-ab95765-1.gif)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab95765 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt: Use 0.25-0.5µg for 105-8 cells. Final volume of 100 µl.
Target
Function
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Tissue specificity
Predominantly expressed in monocytes and granulocytes.
Sequence similarities
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
Domain
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Cellular localization
Membrane.
Target information above from: UniProt accessionP20702
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 95 alpha chain antibody
- 95 antibody
- CD 11c antibody
see all
Database links
- Entrez Gene: 16411 Mouse
- SwissProt: Q9QXH4 Mouse
- Unigene: 22378 Mouse
Anti-CD11c antibody [N418] (Biotin) images:
Flow Cytometry - CD11c antibody [N418] (Biotin) (ab95765)
ab95765 at 0.25µg dilution staining CD11c in C57BL/6 splenocytes by Flow Cytometry (shown in blue) followed by Streptavidin PE.
References for Anti-CD11c antibody [N418] (Biotin) (ab95765)
This product has been referenced in:
- Xin KQ et al. Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells. J Virol 80:11899-910 (2006).Read more (PubMed: 17005662) »
- Ohteki T et al. Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo. J Exp Med 203:2329-38 (2006).Read more (PubMed: 16966429) »
See all 8 publications for this product
Publishing research using ab95765? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"