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Product Name
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CD15 antibody [MEM-158]
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See all CD15 antibodies (25)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [MEM-158] to CD15
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Immunogen
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Tissue / cell preparation (Human granulocytes).
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Reacts with
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Hu
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Does not react with
(species key)
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Mk, Pig
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Specificity
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Human CD15 antigen.
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Tested applications
(see key)
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Flow Cyt, IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use at an assay dependant concentration.
IP: Use at an assay dependant concentration.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Golgi apparatus, Golgi stack membrane; Type II membrane protein. Membrane bound form in trans cisternae of Golgi.
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Research areas
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Stem Cells >> Endothelial Progenitors >> Endothelial Markers
Cancer >> Tumor immunology >> CD markers
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Cell Type Markers >> CD >> Adhesion
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
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Relevance
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The CD15 antigen is expressed on approximately 90% human circulating granulocytes (membranes and granules), 30 to 60% of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The hapten occurs also in glycolipids. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.
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CD15 antibody [MEM-158] (ab665) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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MEM-158
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Isotype
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IgM
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Purity
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>95% by SDS-PAGE
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Storage buffer
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Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Purified from ascites by precipitation and DEAE-chromatography.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD15 antibody [MEM-158] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for CD15 antibody [MEM-158] (ab665)
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This product has been used in:
Kishimoto T. et al. (Eds.) Leucocyte typing VI. Garland Publishing Inc. : (1997).
If you publish research using ab665 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CD15
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CD15 antibody [MEM-158] - more information
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Contact Abcam with a Technical Enquiry about CD15 antibody [MEM-158] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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