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Anti-CD15 antibody [MY-1] (ab754)

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Overview

Product name

Anti-CD15 antibody [MY-1]
See all CD15 products (30) ...

Description

Mouse monoclonal [MY-1] to CD15

Specificity

The specificity of this antibody is similar to antibodies Leu-M1, TÜ 9 and VIM-D5. It reacts with an antigen located on mature granulocytes and on Hodgkin and Reed Sternberg cells.

Tested applications

IHC-P, IHC-Frmore details

Cross reactivity

Reacts with

Human

Immunogen

Purified neutrophils from normal human peripheral blood.

Epitope

This antibody recognizes an epitope involving the carbohydrate sequence 3 fucosyl N acetyllacetosamine.

Positive control

Tonsil.

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, Tissue culture supernatant

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

MY-1

Isotype

IgM

Light chain type

kappa

Research areas

Stem Cells >> Endothelial Progenitors >> Endothelial Markers
Cancer >> Tumor immunology >> CD markers
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Cell Type Markers >> CD >> Adhesion
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD15 antibody [MY-1] (ab754)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD15 antibody [MY-1] (ab754) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

Immunohistochemistry: 1 / 10 - 1 / 25 for 30 - 60 mins at RT (ABC method).
Not tested in other applications.

Optimal dilutions / concentrations should be determined by the end user.

Target

Function

May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.

Pathway

Protein modification; protein glycosylation.

Sequence similarities

Belongs to the glycosyltransferase 10 family.

Cellular localization

Golgi apparatus > Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi.

Target information above from: UniProt accessionP22083 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Alpha (1,3) fucosyltransferase antibody
  • Alpha 13 fucosyltransferase FucT antibody
  • Alpha-(1,3)-fucosyltransferase antibody
  • ELAM ligand fucosyltransferase antibody
  • ELAM-1 ligand fucosyltransferase antibody
  • ELAM1 ligand fucosyltransferase antibody
  • ELFT antibody
  • FCT3A antibody
  • Fuc-TIV antibody
  • Fucosyltransferase 4 alpha 1 3 fucosyltransferase myeloid specific antibody
  • Fucosyltransferase 4 antibody
  • Fucosyltransferase IV antibody
  • FucT IV antibody
  • FucT-IV antibody
  • FUCTIV antibody
  • FUT4 antibody
  • FUT4_HUMAN antibody
  • Galactoside 3 L fucosyltransferase antibody
  • Galactoside 3-L-fucosyltransferase antibody
  • LeX antibody
  • SSEA 1 antibody
  • SSEA1 antibody
  • Stage specific embryonic antigen 1 antibody
see all

Database links

see all

Anti-CD15 antibody [MY-1] images:

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD15 antibody [MY-1] (ab754)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD15 antibody [MY-1] (ab754)

ab754 at a dilution of 1/100 staining CD15 from human bronchus sections by Immunohistochemistry (Paraffin-embedded sections). The antibody was incubated with the tissue for 2 hours and then detected with an Alexa-Fluor®  488 conjugated anti-mouse IgM antibody.

This image is courtesy of an Abreview submitted by an anonymous researcher on 12 December 2005.

See Abreview

References for Anti-CD15 antibody [MY-1] (ab754)

This product has been referenced in:

  • Fernandez-L Aet al. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev 23:2729-41 (2009). IHC-P; Mouse.Read more (PubMed: 19952108) »

See 1 publication for this product

Publishing research using ab754? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"