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Products:Immunology >> Adaptive Immunity >> T Cells >> CD
Overview
Product name
Anti-CD1a antibody [HI149]
See all CD1a products (22) ...
Description
Mouse monoclonal [HI149] to CD1a
Specificity
CD1a antigen (human)
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Human
Immunogen
Tissue / cell preparation (Human thymocytes).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
>95% by SDS-PAGE
Purification notes
Purified from ascites by protein G-affinity chromatography.
Clonality
Monoclonal
Clone number
HI149
Myeloma
unknown
Isotype
IgG1
Light chain type
unknown
Research areas
Immunology >> Adaptive Immunity >> T Cells >> CD
Applications
Show applications key
Our Abpromise guarantee covers the use of ab2574 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt
Application notes
Flow Cyt: Use at an assay dependant concentration.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Tissue specificity
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
Sequence similarities
Contains 1 Ig-like (immunoglobulin-like) domain.
Cellular localization
Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts.
Target information above from: UniProt accessionP06126
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CD 1a antibody
- CD1 antibody
- CD1a antibody
see all
Database links
- Entrez Gene: 909 Human
- Omim: 188370 Human
- SwissProt: P06126 Human
- Unigene: 1309 Human
References for Anti-CD1a antibody [HI149] (ab2574)
This product has been referenced in:
- Schlossman (Eds.) et al. Leucocyte typing V. Oxford University Press : (1995).Read more (PubMed: ) »
See 1 publication for this product
Publishing research using ab2574? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"