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Product Name 

CD1a antibody [NA1/34-HLK]

 

See all CD1a antibodies (15)...

Product type 

Primary antibodies

Description 

Mouse monoclonal [NA1/34-HLK] to CD1a

Immunogen 

Thymocytes (Human).

Reacts with 
(species key)

Hu, Dog, Mk

Specificity 

ab24055 recognises the human CD1a cell surface glycoprotein, a 49kD molecule expressed in association with beta 2 microglobulin. CD1a is expressed strongly by cortical thymocytes, and also by Langerhans cells and interdigitating cells.
NA1/34 does not precipitate out B2m, and SDS PAGE experiments performed by McMichael, A.J.et al.(1979) suggest that NA1/34 recognises a single protein component. From this information it seems very likely that the epitope is not found on the B2m part of the protein.

Tested applications 
(see key)

Flow Cyt


Abreviews 

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Application notes 
(see key)

Recommended dilutions
Flow Cyt: 1/50 - 1/100. Use 10µl of suggeted dilution for 106 cells in 100ul

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cell Membrane; type I membrane protein.

Research areas 

Immunology >> Adaptive Immunity >> T Cells >> CD

Relevance 

CD1a is a non polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin. CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells. CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X.

 

CD1a antibody [NA1/34-HLK] (ab24055)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

909    (Human)

GeneCard

    

GC01P155440    (Human)

Omim

    

188370    (Human)

SwissProt

    

P06126    (Human)

Unigene

    

1309    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

NA1/34-HLK

Myeloma 

NS1/1-Ag4-1

Isotype 

IgG2a

Purity 

IgG fraction

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified IgG prepared by ion exchange chromatography

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD1a antibody [NA1/34-HLK] is on this datasheet. But please do contact us if you would like any reassurance!



References for CD1a antibody [NA1/34-HLK] (ab24055)

Specific publication references   This clone has been used in: (two most recent references)

Yoshino N et al. Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp Anim 49:97-110 (2000). PubMed: 10889948

Galkowska H et al. Reactivity of antibodies directed against human antigens with surface markers on canine leukocytes. Vet Immunol Immunopathol 53:329-34 (1996). PubMed: 8969052


See all 4 publication references for this product.


If you publish research using ab24055 please let us know so that we can cite the reference on this datasheet.

 

Search PubMed (MEDLINE) for references to CD1a

 

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Other CD1a Antibodies

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