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Products:Immunology >> Adaptive Immunity >> T Cells >> CD
Overview
Product name
Anti-CD1a antibody
See all CD1a products (22) ...
Description
Rabbit polyclonal to CD1a
Specificity
This antibody is specific to CD1a.
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment, corresponding to amino acids 19-327 of Human CD1a (Peptide available as ab38220.)
Positive control
Human tonsil for Western blot.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 10mM PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
This antibody is affinity purified.
Clonality
Polyclonal
Isotype
IgG
Research areas
Immunology >> Adaptive Immunity >> T Cells >> CD
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Western blot - CD1a antibody (ab27453)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab27453 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1 - 2 µg/ml for 2 hours at room temperature. Predicted molecular weight: 37 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Tissue specificity
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
Sequence similarities
Contains 1 Ig-like (immunoglobulin-like) domain.
Cellular localization
Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts.
Target information above from: UniProt accessionP06126
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CD 1a antibody
- CD1 antibody
- CD1a antibody
see all
Database links
- Entrez Gene: 909 Human
- Omim: 188370 Human
- SwissProt: P06126 Human
- Unigene: 1309 Human
Anti-CD1a antibody images:
Western blot - CD1a antibody (ab27453)
Anti-CD1a antibody (ab27453) at 1/25 dilution + K562 cell lysate
Predicted band size : 37 kDa
Observed band size : 49 kDa (why is the actual band size different from the predicted?)
References for Anti-CD1a antibody (ab27453)
ab27453 has not yet been referenced specifically in any publications.
Publishing research using ab27453? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"