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Anti-CD1b+c antibody [B-B5] - Azide free (ab46863)

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Overview

Product name

Anti-CD1b+c antibody [B-B5] - Azide free
See all CD1b+c products (3) ...

Description

Mouse monoclonal [B-B5] to CD1b+c - Azide free

Tested applications

Flow Cytmore details

Cross reactivity

Reacts with

Human

Immunogen

Thymus cells and Jurkat cell line

Positive control

Molt 4 cell line

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: PBS

Concentration

Concentration information loading...

Purity

Ion Exchange Chromatography

Purification notes

Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free

Clonality

Monoclonal

Clone number

B-B5

Myeloma

x63-Ag8.653

Isotype

IgG1

Research areas

Immunology >> Immunoglobulins >> Receptors
Immunology >> Cell Type Markers >> CD >> Non-lineage
Immunology >> Adaptive Immunity >> T Cells >> CD

  • Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab46863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

CD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.

Cellular localization

Single-pass type I membrane protein.

Alternative names

  • CD1 antibody
  • CD1B antigen antibody
  • CD1b molecule antibody
  • CD1C antigen antibody
  • CD1c molecule antibody
  • R1 antibody
  • R7 antibody
see all

Database links

Anti-CD1b+c antibody [B-B5] - Azide free images:

  Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)

Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)

A typical staining pattern with ab46863 monoclonal antibody of Molt 4 cell line.

References for Anti-CD1b+c antibody [B-B5] - Azide free (ab46863)

This product has been referenced in:

  • Groot Fet al. Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction. J Virol 79:3009-15 (2005).Read more (PubMed: 15709021) »

See 1 publication for this product

Publishing research using ab46863? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"