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Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)
![Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)](/ps/datasheet/images/ab46863_1.gif)
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Product Name
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CD1b+c antibody [B-B5] - Azide free
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See all CD1b+c antibodies (3)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [B-B5] to CD1b+c - Azide free
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Immunogen
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Thymus cells and Jurkat cell line
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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Flow Cyt
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Molt 4 cell line
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Cellular localization
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Single-pass type I membrane protein.
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Research areas
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Immunology >> Immunoglobulins >> Receptors
Immunology >> Cell Type Markers >> CD >> Non-lineage
Immunology >> Adaptive Immunity >> T Cells >> CD
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Relevance
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CD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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B-B5
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Myeloma
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x63-Ag8.653
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Isotype
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IgG1
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Purity
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Ion Exchange Chromatography
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Storage buffer
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Preservative: None
Constituents: PBS
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Purification notes
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Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD1b+c antibody [B-B5] - Azide free is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CD1b+c antibody [B-B5] - Azide free images, references, products related to ab46863 and other tools.
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CD1b+c antibody [B-B5] - Azide free images:
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 Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)
A typical staining pattern with ab46863 monoclonal antibody of Molt 4 cell line.
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References for CD1b+c antibody [B-B5] - Azide free (ab46863)
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This clone has been used in:
Groot F et al. Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction. J Virol 79:3009-15 (2005). PubMed: 15709021
If you publish research using ab46863 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CD1b+c
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CD1b+c antibody [B-B5] - Azide free - more information
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Customer reviews (feedback) regarding CD1b+c antibody [B-B5] - Azide free |
Customer FAQs regarding CD1b+c antibody [B-B5] - Azide free |
Protocols for CD1b+c antibody [B-B5] - Azide free |
Price and availability of products related to CD1b+c antibody [B-B5] - Azide free |
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CD1b+c antibody [B-B5] - Azide free - related products:
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CD1b+c antibody [B-B5] - Azide free - other tools:
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Contact Abcam with a Technical Enquiry about CD1b+c antibody [B-B5] - Azide free |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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![Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)](/index.html?datasheet=46863#ab46863_1.gif)
