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Overview

  • Product nameAnti-CD1b+c antibody [B-B5] - Azide freeSee all CD1b+c primary antibodies ...
  • Description
    Mouse monoclonal [B-B5] to CD1b+c - Azide free
  • Tested applicationsFlow Cyt more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Thymus cells and Jurkat cell line

  • Positive controlMolt 4 cell line

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityIon Exchange Chromatography
  • Purification notesSterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free
  • Clonality Monoclonal
  • Clone numberB-B5
  • Myelomax63-Ag8.653
  • IsotypeIgG1
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab46863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Flow Cyt Flow Cyt: Use at an assay dependent dilution.

Target

  • RelevanceCD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
  • Cellular localizationSingle-pass type I membrane protein.
  • Database links
    • Alternative names
        CD1 antibodyCD1B antigen antibodyCD1b molecule antibody
        CD1C antigen antibodyCD1c molecule antibodyR1 antibodyR7 antibody
      see all

    Anti-CD1b+c antibody [B-B5] - Azide free images

    • Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)
      Flow Cytometry - CD1b+c antibody [B-B5] - Azide free (ab46863)
      A typical staining pattern with ab46863 monoclonal antibody of Molt 4 cell line.

    References for Anti-CD1b+c antibody [B-B5] - Azide free (ab46863)

    This product has been referenced in:
    • Groot F  et al. Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction. J Virol 79:3009-15 (2005). Read more (PubMed: 15709021) »

    See 1 Publication for this product

    Publishing research using ab46863 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"