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Flow Cytometry - CD1b+c antibody [B-B5] (FITC) (ab27336)
![Flow Cytometry - CD1b+c antibody [B-B5] (FITC) (ab27336)](/ps/datasheet/images/ab27336.gif)
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Product Name
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CD1b+c antibody [B-B5] (FITC)
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See all CD1b+c antibodies (3)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [B-B5] to CD1b+c (FITC)
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Immunogen
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Thymus cells and Jurkat cell line (Human)
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Reacts with
(species key)
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Hu
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Specificity
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This antibody is specific for CD1b and c proteins.
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Tested applications
(see key)
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Flow Cyt
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use 10µl for 106 cells or 100 µl of whole blood.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Single-pass type I membrane protein.
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Research areas
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Immunology >> Immunoglobulins >> Receptors
Immunology >> Cell Type Markers >> CD >> Non-lineage
Immunology >> Adaptive Immunity >> T Cells >> CD
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Relevance
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CD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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B-B5
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Myeloma
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x63-Ag8.653
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Isotype
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IgG1
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Purity
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Ion Exchange Chromatography
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Conjugation
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Fluorescein
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD1b+c antibody [B-B5] (FITC) is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CD1b+c antibody [B-B5] (FITC) images, references, products related to ab27336 and other tools.
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CD1b+c antibody [B-B5] (FITC) images:
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 Flow Cytometry - CD1b+c antibody [B-B5] (FITC) (ab27336)
Staining pattern of Molt 4 cell line with ab27336 at 10ul/106 cells.
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References for CD1b+c antibody [B-B5] (FITC) (ab27336)
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This product has been used in:
Sancho D et al. Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin. J Clin Invest 118:2098-2110 (2008). Flow Cyt; Human. PubMed: 18497879
If you publish research using ab27336 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CD1b+c
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CD1b+c antibody [B-B5] (FITC) - more information
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Customer reviews (feedback) regarding CD1b+c antibody [B-B5] (FITC) |
Customer FAQs regarding CD1b+c antibody [B-B5] (FITC) |
Protocols for CD1b+c antibody [B-B5] (FITC) |
Price and availability of products related to CD1b+c antibody [B-B5] (FITC) |
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CD1b+c antibody [B-B5] (FITC) - related products:
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CD1b+c antibody [B-B5] (FITC) - other tools:
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Contact Abcam with a Technical Enquiry about CD1b+c antibody [B-B5] (FITC) |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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![Flow Cytometry - CD1b+c antibody [B-B5] (FITC) (ab27336)](/index.html?datasheet=27336#ab27336.gif)
