Anti-CD1b+c antibody [B-B5] (FITC) (ab27336)
- Product nameAnti-CD1b+c antibody [B-B5] (FITC)See all CD1b+c primary antibodies ...
- DescriptionMouse monoclonal [B-B5] to CD1b+c (FITC)
- SpecificityThis antibody is specific for CD1b and c proteins.
- Tested applicationsFlow Cyt more details
- Species reactivityReacts with: Human
Thymus cells and Jurkat cell line (Human)
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.1% Sodium Azide
Constituents: 1% BSA, PBS
- Concentration information loading...
- PurityIon Exchange Chromatography
- Clonality Monoclonal
- Clone numberB-B5
- Research Areas
Our Abpromise guarantee covers the use of ab27336 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- RelevanceCD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
- Cellular localizationSingle-pass type I membrane protein.
- CD1 antibodyCD1B antigen antibodyCD1b molecule antibody
- CD1C antigen antibodyCD1c molecule antibodyR1 antibodyR7 antibody
Anti-CD1b+c antibody [B-B5] (FITC) images
Staining pattern of Molt 4 cell line with ab27336 at 10ul/106 cells.
References for Anti-CD1b+c antibody [B-B5] (FITC) (ab27336)
This product has been referenced in:
- Sancho D et al. Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin. J Clin Invest 118:2098-2110 (2008). Flow Cyt ; Human . Read more (PubMed: 18497879) »