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Overview

  • Product nameAnti-CD1b+c antibody [B-B5] (FITC)See all CD1b+c primary antibodies ...
  • Description
    Mouse monoclonal [B-B5] to CD1b+c (FITC)
  • ConjugationFITC
  • SpecificityThis antibody is specific for CD1b and c proteins.
  • Tested applicationsFlow Cyt more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Thymus cells and Jurkat cell line (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab27336 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Flow Cyt
  • Application notesFlow Cyt: Use 10µl for 106 cells or 100 µl of whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • RelevanceCD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
    • Cellular localizationSingle-pass type I membrane protein.
    • Database links
      • Alternative names
          CD1 antibodyCD1B antigen antibodyCD1b molecule antibody
          CD1C antigen antibodyCD1c molecule antibodyR1 antibodyR7 antibody
        see all

      Anti-CD1b+c antibody [B-B5] (FITC) images

      • Flow Cytometry - CD1b+c antibody [B-B5] (FITC) (ab27336)
        Flow Cytometry - CD1b+c antibody [B-B5] (FITC) (ab27336)
        Staining pattern of Molt 4 cell line with ab27336 at 10ul/106 cells.

      References for Anti-CD1b+c antibody [B-B5] (FITC) (ab27336)

      This product has been referenced in:
      • Sancho D  et al. Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin. J Clin Invest 118:2098-2110 (2008). Flow Cyt ; Human . Read more (PubMed: 18497879) »

      See 1 Publication for this product

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"