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Products:Immunology >> Adaptive Immunity >> T Cells >> CD
Overview
Product name
Anti-CD1c antibody [M241]
See all CD1c products (2) ...
Description
Mouse monoclonal [M241] to CD1c
Tested applications
IP, RIDmore details
Cross reactivity
Reacts with
Human
Immunogen
MOLT 4 cell line.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
M241
Isotype
IgG1
Research areas
Immunology >> Immunoglobulins >> Receptors
Immunology >> Adaptive Immunity >> T Cells >> CD
Applications
Show applications key
Our Abpromise guarantee covers the use of ab18216 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: Use at an assay dependent dilution.
RID: Use at an assay dependent dilution.
Target
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Tissue specificity
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Sequence similarities
Contains 1 Ig-like (immunoglobulin-like) domain.
Cellular localization
Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes.
Target information above from: UniProt accessionP29017
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- BDCA1 antibody
- CD1 antibody
- CD1A antibody
see all
Database links
- Entrez Gene: 911 Human
- Omim: 188340 Human
- SwissProt: P29017 Human
- Unigene: 132448 Human
References for Anti-CD1c antibody [M241] (ab18216)
This product has been referenced in:
- Small TNet al. Characterization of B cells in severe combined immunodeficiency disease. Hum Immunol 25:181-93 (1989).Read more (PubMed: 2670851) »
- Knowles RW & Bodmer WF A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin. Eur J Immunol 12:676-81 (1982).Read more (PubMed: 6754387) »
See all 2 publications for this product
Publishing research using ab18216? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"