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Overview

  • Product nameAnti-CD1d antibody [1B1]See all CD1d primary antibodies ...
  • Description
    Rat monoclonal [1B1] to CD1d
  • Specificityab95734 detects ß2-m associated CD1d
  • Tested applicationsFlow Cyt more details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse C57Bl/6 thymocytes

  • Positive controlMouse splenocyte suspensions

Properties

Applications

Our Abpromise guarantee covers the use of ab95734 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Flow Cyt Flow Cyt: Use 1µg for 105-8 cells. in a final volume of 100 µL

Target

  • FunctionAntigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
  • Tissue specificityExpressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
  • Sequence similaritiesContains 1 Ig-like (immunoglobulin-like) domain.
  • Cellular localizationCell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.

    • Target information above from: UniProt accession P15813 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Antigen-presenting glycoprotein CD1d antibodyCD1.1 antibodyCD1A antibody
        CD1d antibodyCD1D antigen antibodyCD1D antigen d polypeptide antibodyCD1d molecule antibodyCD1D_HUMAN antibodyCd1d1 antibodydifferentiation antigen CD1 alpha 3 antibodyHMC class I antigen like glycoprotein CD1D antibodyLy 38 antibodyMGC34622 antibodyR3 antibodyR3G1 antibodyT cell surface glycoprotein CD1d antibodyThymocyte antigen CD1D antibody
      see all

    Anti-CD1d antibody [1B1] images

    • Flow Cytometry - CD1d antibody [1B1] (ab95734)
      Flow Cytometry - CD1d antibody [1B1] (ab95734)
      ab95734 at 1 µg per test staining BALB/c splenocytes (filled histogram) by Flow Cytometry. The control utilised 1.0 µg of Rat IgG2b Isotype Control (open histogram).

    References for Anti-CD1d antibody [1B1] (ab95734)

    This product has been referenced in:
    • Szalay G  et al. Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-beta 2 and Th1 cytokines and ameliorates listeriosis in mice. J Immunol 162:6955-8 (1999). Read more (PubMed: 10358132) »
    • Burdin N  et al. Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes. J Immunol 161:3271-81 (1998). Read more (PubMed: 9759842) »

    See all 2 Publications for this product

    Publishing research using ab95734 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"