Anti-CD1d antibody [WTH1] (FITC) (ab119897)
Overview
- Product nameAnti-CD1d antibody [WTH1] (FITC)See all CD1d primary antibodies ...
- DescriptionMouse monoclonal [WTH1] to CD1d (FITC)
- ConjugationFITC
- SpecificityBinds with high affinity to the mature CD1d heavy chain independently of beta-2-microglobulin.
- Tested applicationsFlow Cyt more details
- Species reactivityReacts with: Mouse, Rat
- Immunogen
Rat CD1d-transduced M12.4.1.C3 cells.
- Positive controlRat thymocytes.
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... - PurityIgG fraction
- Primary antibody notes Clone WTH1 efficiently blocks rat and mouse invariant natural killer T cell (iNKT cell) response to a-GalCer (an antigen for iNKT cells).
- Clonality Monoclonal
- Clone numberWTH1
- IsotypeIgG2a
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Research Areas
Applications
Our Abpromise guarantee covers the use of ab119897 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| Flow Cyt | Flow Cyt: Use 10µl for 106 cells. in 100 µl. |
Target
- FunctionAntigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
- Tissue specificityExpressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
- Sequence similaritiesContains 1 Ig-like (immunoglobulin-like) domain.
- Cellular localizationCell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
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Database links
- Entrez Gene: 12479 Mouse
- Entrez Gene: 25109 Rat
- SwissProt: P11609 Mouse
- SwissProt: Q63493 Rat
- Unigene: 1894 Mouse
- Unigene: 11120 Rat
Target information above from: UniProt accession
P15813
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Antigen-presenting glycoprotein CD1d antibodyCD1.1 antibodyCD1A antibody
- CD1d antibodyCD1D antigen antibodyCD1D antigen d polypeptide antibodyCD1d molecule antibodyCD1D_HUMAN antibodyCd1d1 antibodydifferentiation antigen CD1 alpha 3 antibodyHMC class I antigen like glycoprotein CD1D antibodyLy 38 antibodyMGC34622 antibodyR3 antibodyR3G1 antibodyT cell surface glycoprotein CD1d antibodyThymocyte antigen CD1D antibody
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Anti-CD1d antibody [WTH1] (FITC) images
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Staining of rat thymocytes with ab119897 at 10µl X 106 cells.
References for Anti-CD1d antibody [WTH1] (FITC) (ab119897)
This product has been referenced in:
- Monzon-Casanova E et al. CD1d expression in paneth cells and rat exocrine pancreas revealed by novel monoclonal antibodies which differentially affect NKT cell activation. PLoS One 5: (2010). Read more (PubMed: 20927351) »
![Flow Cytometry - Anti-CD1d antibody [WTH1] (FITC) (ab119897) Flow Cytometry - Anti-CD1d antibody [WTH1] (FITC) (ab119897)](http://a.abcam.com/ps/datasheet/images/119/ab119897/CD1d-Primary-antibodies-ab119897-1.jpg)