PE/Cy7® Anti-CD23 antibody [2G8] (ab59456)
Key features and details
- PE/Cy7® Rat monoclonal [2G8] to CD23
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE/Cy7®. Ex: 496nm, Em: 774nm
- Isotype: IgG2a
Overview
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Product name
PE/Cy7® Anti-CD23 antibody [2G8]
See all CD23 primary antibodies -
Description
PE/Cy7® Rat monoclonal [2G8] to CD23 -
Host species
Rat -
Conjugation
PE/Cy7®. Ex: 496nm, Em: 774nm -
Specificity
This antibody reacts with the CD23 low affinity IgE Fc receptor. -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to CD23. FcεR isolated from B cell lymphoma cell line M12.4.5
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General notes
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.1
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Also contains stabilising agent. -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
2G8 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab59456 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
ab154460 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. ab154460 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Target
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Function
This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). -
Sequence similarities
Contains 1 C-type lectin domain. -
Post-translational
modificationsN- and O-glycosylated. -
Cellular localization
Cell membrane. Secreted. Also exists as a soluble excreted form. - Information by UniProt
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Database links
- Entrez Gene: 14128 Mouse
- SwissProt: P20693 Mouse
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Alternative names
- Blast 2 antibody
- BLAST-2 antibody
- Blast2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab59456 has been referenced in 2 publications.
- Kaku H et al. CD25 (+) B-1a Cells Express Aicda. Front Immunol 8:672 (2017). Flow Cyt ; Mouse . PubMed: 28676801
- Kaku H et al. A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production. J Immunol 193:5904-13 (2014). PubMed: 25392527