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Product name
Anti-CD239 antibody [MM0107-1M39]
See all CD239 products (3) ...
Description
Mouse monoclonal [MM0107-1M39] to CD239
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment (Human) - extracellular region
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.
Clonality
Monoclonal
Clone number
MM0107-1M39
Isotype
IgG2
Research areas
Cardiovascular >> Atherosclerosis >> Thrombosis >> Other
Immunology >> Immunoglobulins >> Receptors
Cardiovascular >> Blood >> Other
Cardiovascular >> Blood >> Blood Cell Antigens
Applications
Show applications key
Our Abpromise guarantee covers the use of ab89142 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000. Predicted molecular weight: 67 kDa.
Target
Function
Laminin alpha-5 receptor. May mediate intracellular signaling.
Tissue specificity
Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
Sequence similarities
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
Developmental stage
Is under developmental control in liver and may also be regulated during differentiation in other tissues. Up-regulated following malignant transformation in some cell types.
Post-translational
modifications
Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin.
Cellular localization
Membrane.
Target information above from: UniProt accessionP50895
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Antigen identified by monoclonal antibody F8 antibody
- AU antibody
- Auberger B antigen antibody
see all
Database links
- Entrez Gene: 4059 Human
- Omim: 612773 Human
- SwissProt: P50895 Human
- Unigene: 625725 Human
References for Anti-CD239 antibody [MM0107-1M39] (ab89142)
ab89142 has not yet been referenced specifically in any publications.
Publishing research using ab89142? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"