CD24 antibody [SN3] (Phycoerythrin), prediluted (ab30351)

Product Name 

CD24 antibody [SN3] (Phycoerythrin), prediluted

Product type 

Primary antibodies

Description 

Mouse monoclonal [SN3] to CD24, prediluted (Phycoerythrin)

Immunogen 

Glycoproteins purified from human NALM-1 cell line

Reacts with 
(species key)

Hu

Specificity 

ab30351 recognises CD24 cell surface antigen, a heavily glycosylated molecule. CD24 is expressed by granulocytes and B lymphocytes, and by some activated T cells and T cell malignancies.

Tested applications 
(see key)

Flow Cyt

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
Flow Cyt: Use 10µl for 10⁶ cells or 100ul whole blood.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cell Membrane, attached by a GPI anchor.

Research areas 

Cancer >> Cancer Metabolism >> Cellular metabolic process
Cancer >> Cancer Metabolism >> Response to hypoxia
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Erythrocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Neutrophil Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Dendritic Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Cancer >> Tumor biomarkers >> Tumor antigens
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Adaptive Immunity >> B Cells >> CD
Neuroscience >> Cell Type Marker >> Neural Stem Cell marker

Relevance 

CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer

Database links 

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

SN3

Isotype 

IgG1

Purity 

Protein G purified

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Conjugation 

Phycoerythrin

Storage instructions 

Store at +4°C in the dark. Do not freeze.

See below for CD24 antibody [SN3] (Phycoerythrin), prediluted images, references, products related to ab30351 and other tools.

CD24 antibody [SN3] (Phycoerythrin), prediluted images:

References for CD24 antibody [SN3] (Phycoerythrin), prediluted (ab30351)

  This clone has been used in: (two most recent references)

Barcos M et al. Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3. Hematol Oncol 4:251-9 (1986). PubMed: 3493967

Fukukawa T et al. New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells. Exp Hematol 14:850-5 (1986). PubMed: 3489635
If you publish research using ab30351 please let us know so that we can cite the reference on this datasheet.

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