Anti-CD34 antibody [B-G25] (ab27335)

Overview

• Product nameAnti-CD34 antibody [B-G25]See all CD34 primary antibodies ...
• Description
  Mouse monoclonal [B-G25] to CD34
• SpecificityThis antibody is specific for CD34.
• Tested applicationsFlow Cyt more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  KG-1a cell line.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.1% Sodium Azide
  Constituents: 1% BSA, PBS
• Concentration information loading...
• PurityIon Exchange Chromatography
• Clonality Monoclonal
• Clone numberB-G25
• Myelomax63-Ag8.653
• IsotypeIgG1
• Research Areas
  • Developmental Biology
  • Lineage specification
  • Mesoderm

  • Stem Cells
  • Endothelial Progenitors
  • Endothelial Markers

  • Stem Cells
  • Hematopoietic Progenitors
  • Surface Molecules

  • Stem Cells
  • Lineage Markers
  • Mesoderm

  • Stem Cells
  • Hematopoietic Progenitors
  • Hematopoietic Stem Cells
  • HSC markers

  • Stem Cells
  • Mesenchymal Stem Cells
  • Negative Markers

  • Cancer
  • Tumor biomarkers
  • Other

  • Cardiovascular
  • Heart
  • Cardiogenesis
  • Stem cells

  • Immunology
  • Cell Type Markers
  • CD
  • Myeloid Cells

  • Neuroscience
  • Cell Type Marker
  • Neuron marker
  • Soma marker

Applications

Target

• FunctionPossible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
• Tissue specificitySelectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
• Sequence similaritiesBelongs to the CD34 family.
• Developmental stageOn early hematopoietic progenitor cells.
• Post-translational
  modificationsHighly glycosylated.
  Phosphorylated on serine residues by PKC.
• Cellular localizationMembrane.

Target information above from: UniProt accession P28906 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 947 Human
  • Omim: 142230 Human
  • SwissProt: P28906 Human
  • Unigene: 374990 Human

• Alternative names
  CD34 antibodyCd34 antibodyCD34 antigen antibody

  CD34 molecule antibodyCD34_HUMAN antibodyCluster designation 34 antibodyHematopoietic progenitor cell antigen CD34 antibodyHPCA1 antibodyMucosialin antibodyOTTHUMP00000034733 antibodyOTTHUMP00000034734 antibody

  see all

Anti-CD34 antibody [B-G25] images

• 

  Flow Cytometry / FACS - CD34 antibody [B-G25] (ab27335)
  Ab27335, staining CD34 by FACS.