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Anti-CD36 [CRF D-2712] antibody (ab125116)

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Overview

  • Product nameAnti-CD36 [CRF D-2712] antibodySee all CD36 primary antibodies ...
  • Description
    Mouse monoclonal [CRF D-2712] to CD36
  • Tested applicationsWB, IP, Flow Cyt, ICC/IF, Functional Studies more details
  • Species reactivity
    Reacts with: Mouse, Rat

Applications

Our Abpromise guarantee covers the use of ab125116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/25. Predicted molecular weight: 53 kDa.
IP IP: Use at an assay dependent dilution.
Flow Cyt Flow Cyt: 1/25.
ICC/IF ICC/IF: Use at an assay dependent dilution.
Functional Studies FuncS: Use at an assay dependent concentration.

Target

  • FunctionSeems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic efects.
  • Involvement in diseaseDefects in CD36 are the cause of platelet glycoprotein IV deficiency (PG4D)[MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal.
    Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7) [MIM:610938].
  • Sequence similaritiesBelongs to the CD36 family.
  • Post-translational
    modifications    N-glycosylated and O-glycosylated with a ratio of 2:1.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P16671 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Adipocyte membrane protein antibodyCD36 antibodyCD36 antigen (collagen type I receptor, thrombospondin receptor) antibody
        CD36 antigen antibodyCD36 molecule (thrombospondin receptor) antibodyCD36 molecule antibodyCD36_HUMAN antibodyCHDS7 antibodyCluster determinant 36 antibodyCollagen receptor, platelet antibodyFAT antibodyFatty acid translocase antibodyFatty acid transport protein antibodyGlycoprotein IIIb antibodyGP IIIb antibodyGP3B antibodyGP4 antibodyGPIIIB antibodyGPIV antibodyLeukocyte differentiation antigen CD36 antibodyMGC108510 antibodyMGC91634 antibodyPAS 4 protein antibodyPAS IV antibodyPAS-4 antibodyPASIV antibodyPlatelet collagen receptor antibodyPlatelet glycoprotein 4 antibodyPlatelet glycoprotein IV antibodyscarb3 antibodyScavenger receptor class B member 3 antibodyThrombospondin receptor antibody
      see all

    References for Anti-CD36 [CRF D-2712] antibody (ab125116)

    ab125116 has not yet been referenced specifically in any publications.

    Publishing research using ab125116 ? Please let us know so that we can cite the reference in this datasheet

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    Submit an Abreview for ab125116 Submit a Question for ab125116

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    Votes: Highest First

    I would have a question concerning the product ab125116. Is this antibody azide-free? What is the level of its contamination with endotoxin?

    I can confirm that the formulation for ab125116 CD36 antibody [CRF D-2712] is culture medium with low endotoxin level. The antibody does not contain azide.

    The endotoxin level of one of the recent batches is 1.14 EU/ml.

    What is the storage buffer constituents for this antibody?

    Thank you for contacting us.

    Lab has confirmed that the antibody is in cell culture medium.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"