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Anti-CD38 antibody [38C03], prediluted (ab75231)

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Overview

  • Product nameAnti-CD38 antibody [38C03], predilutedSee all CD38 primary antibodies ...
  • Description
    Mouse monoclonal [38C03] to CD38, prediluted
  • Tested applicationsIHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment encoding the extracellular domain of Human CD38.

  • Positive controlHuman tonsil.
  • General notesClone designation 38C03 is the same as SPC32.

Applications

Our Abpromise guarantee covers the use of ab75231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
  • Application notesIHC-P: Ready-to-use. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
    Requires use of a high-sensitivity detection system.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionSynthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
    • Tissue specificityExpressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
    • Sequence similaritiesBelongs to the ADP-ribosyl cyclase family.
    • Developmental stagePreferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
    • Cellular localizationMembrane.

      • Target information above from: UniProt accession P28907 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • FormThere are 2 isoforms produced by alternative splicing.
      • Alternative names
          Acute lymphoblastic leukemia cells antigen CD38 antibodyADP ribosyl cyclase 1 antibodyADP ribosyl cyclase antibody
          ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibodyADP-ribosyl cyclase 1 antibodyCADPr hydrolase 1 antibodyCD 38 antibodyCD38 antibodyCD38 antibodyCD38 antigen (p45) antibodyCD38 antigen antibodyCD38 molecule antibodyCd38-rs1 antibodyCD38_HUMAN antibodyCD38H antibodyCyclic ADP ribose hydrolase antibodyCyclic ADP ribose hydrolase 1 antibodyCyclic ADP-ribose hydrolase 1 antibodyEC 3.2.2.5 antibodyEcto nicotinamide adenine dinucleotide glycohydrolase antibodyI-19 antibodyI19 (mouse) antibodyLymphocyte differentiation antigen CD38 antibodyNAD(+) nucleosidase antibodyNIM-R5 antigen antibodyNIMR5 antigen (mouse) antibodyOTTHUMP00000158633 antibodyOTTHUMP00000217743 antibodyp45 antibodyT10 antibody
        see all

      Anti-CD38 antibody [38C03], prediluted images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD38 antibody [38C03], prediluted (ab75231)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD38 antibody [38C03], prediluted (ab75231)
        Formalin-fixed, paraffin-embedded human tonsil stained with ab75231, using peroxidase-conjugate and AEC chromogen. Note membrane staining of lymphocytes.

      References for Anti-CD38 antibody [38C03], prediluted (ab75231)

      ab75231 has not yet been referenced specifically in any publications.

      Publishing research using ab75231 ? Please let us know so that we can cite the reference in this datasheet

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      I wish to have specific information for the monoclonal antibodies of human CD38 available on your web site. More specifically, I would like to know the nature of the immunogen used to raise those monoclonal antibodies (e.g. amino ...

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      Having contacted the originators of these antibodies, we can let you know the following about the immunogens:

      ab2577: Tissue / cell preparation (Human thymocytes in foetus). According to our information th...

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"