![Flow Cytometry - CD38 antibody [90] (FITC) (ab24978) image](#ab24978_2.jpg)
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Products:Immunology >> Adaptive Immunity >> B Cells >> CD
Overview
Product name
Anti-CD38 antibody [90] (FITC)
See all CD38 products (40) ...
Description
Rat monoclonal [90] to CD38 (FITC)
Conjugation
FITC
Specificity
ab24978 recognises CD38, an immunoregulatory ectoenzyme.
Tested applications
Flow Cyt, IP, IHC-Fr, Cellular activationmore details
Cross reactivity
Reacts with
Mouse
Immunogen
The details of the immunogen for this antibody are not available.
Properties
Form
Liquid
Storage instructions
Store at +4°C in the dark.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
90
Isotype
IgG2a
Light chain type
kappa
Research areas
Cancer >> Cancer Metabolism >> Response to hypoxia
Immunology >> Adaptive Immunity >> Regulatory T Cells
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> NK Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Surface Molecules
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Adaptive Immunity >> B Cells >> CD
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Flow Cytometry - CD38 antibody [90] (FITC) (ab24978)
![Flow Cytometry - CD38 antibody [90] (FITC) (ab24978) image](/ps/datasheet/Images/24/ab24978/ab24978_2.jpg)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab24978 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
Flow Cyt
IP
IHC-Fr
Cellular activation
Application notes
Cellular activation [Induction of B lymphocyte proliferation]: Use at an assay dependent dilution.
Flow Cyt: Use 1µg for 106 cells.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Tissue specificity
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Sequence similarities
Belongs to the ADP-ribosyl cyclase family.
Developmental stage
Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
Cellular localization
Membrane.
Target information above from: UniProt accessionP28907
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Form
There are 2 isoforms produced by alternative splicing.
Alternative names
- Acute lymphoblastic leukemia cells antigen CD38 antibody
- ADP ribosyl cyclase 1 antibody
- ADP ribosyl cyclase antibody
see all
Database links
- Entrez Gene: 12494 Mouse
- SwissProt: P56528 Mouse
- Unigene: 249873 Mouse
Anti-CD38 antibody [90] (FITC) images:
Flow Cytometry - CD38 antibody [90] (FITC) (ab24978)
ab24978 staining mouse (BALB/c) spleen cells by flow cytometery. 1µg antibody was used for 106 cells.
References for Anti-CD38 antibody [90] (FITC) (ab24978)
ab24978 has not yet been referenced specifically in any publications.
Publishing research using ab24978? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"