You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

Anti-CD38 antibody [SPC32] (ab49644)

CodeSizePriceAbpointsAvailability
    
Add to basket
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

Anti-CD38 antibody [SPC32]
See all CD38 products (40) ...

Description

Mouse monoclonal [SPC32] to CD38

Tested applications

IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fusion protein corresponding to the extracellular region of human CD38 molecule.

Positive control

IHC - Tonsil

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

SPC32

Isotype

IgG1

Research areas

Cancer >> Cancer Metabolism >> Response to hypoxia
Immunology >> Adaptive Immunity >> Regulatory T Cells
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> NK Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Surface Molecules
Stem Cells >> Hematopoietic Progenitors >> Hematopoietic Stem Cells >> Human Lineage Negative
Immunology >> Adaptive Immunity >> B Cells >> CD

Applications

Show applications key

Our Abpromise guarantee covers the use of ab49644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    IHC-P

     IHC-P: 1/50 - 1/100.(Not...Read more →

    IHC-P: 1/50 - 1/100.(Note: the recommended fixative is 10% neutral-buffered formalin.High temperature antigen retrieval using 0.01M citrate retrieval solution (pH 6.0) is recommended.)

Target

Function

Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Tissue specificity

Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.

Sequence similarities

Belongs to the ADP-ribosyl cyclase family.

Developmental stage

Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.

Cellular localization

Membrane.

Target information above from: UniProt accessionP28907 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Form

There are 2 isoforms produced by alternative splicing.

Alternative names

  • Acute lymphoblastic leukemia cells antigen CD38 antibody
  • ADP ribosyl cyclase 1 antibody
  • ADP ribosyl cyclase antibody
  • ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody
  • ADP-ribosyl cyclase 1 antibody
  • CADPr hydrolase 1 antibody
  • CD 38 antibody
  • CD38 antibody
  • CD38 antibody
  • CD38 antigen (p45) antibody
  • CD38 antigen antibody
  • CD38 molecule antibody
  • Cd38-rs1 antibody
  • CD38_HUMAN antibody
  • CD38H antibody
  • Cyclic ADP ribose hydrolase antibody
  • Cyclic ADP ribose hydrolase 1 antibody
  • Cyclic ADP-ribose hydrolase 1 antibody
  • EC 3.2.2.5 antibody
  • Ecto nicotinamide adenine dinucleotide glycohydrolase antibody
  • I-19 antibody
  • I19 (mouse) antibody
  • Lymphocyte differentiation antigen CD38 antibody
  • NAD(+) nucleosidase antibody
  • NIM-R5 antigen antibody
  • NIMR5 antigen (mouse) antibody
  • OTTHUMP00000158633 antibody
  • OTTHUMP00000217743 antibody
  • p45 antibody
  • T10 antibody
see all

Database links

References for Anti-CD38 antibody [SPC32] (ab49644)

This product has been referenced in:

  • Willis SNet al. The microenvironment of germ cell tumors harbors a prominent antigen-driven humoral response. J Immunol 182:3310-7 (2009). IHC-P; Human.Read more (PubMed: 19234230) »

See 1 publication for this product

Publishing research using ab49644? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"