|
|
|
|
Western blot - CD4 antibody (ab24800)
(enlarge)
|
|
|
|
|
Product Name
|
CD4 antibody
|
| |
See all CD4 antibodies (101)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to CD4
|
|
Immunogen
|
Recombinant fragment: IGLGIFFCVR CRHRRRQAER MSQIKRLLSE KKTCQCPHRF corresponding to amino acids 412-459 of Human CD4
BLAST 'IGLGIFFCVR CRHRRRQAER MSQIKRLLSE KKTCQCPHRF ' with  or 
|
|
Reacts with
|
Hu
|
|
Predicted to react
(species key)
|
Chmp, CynMk, Mcq, Shp
(Due to sequence homology)
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
WB: Use at a concentration of 1-2 µg/ml. Predicted molecular weight: 59 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
Raji cells. Tonsil
|
|
Cellular localization
|
Cell membrane; Single pass type I membrane protein.
|
|
Research areas
|
Immunology >> Adaptive Immunity >> Regulatory T Cells
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Dendritic Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Immunology >> Adaptive Immunity >> T Cells >> CD
|
|
Relevance
|
CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Immunogen affinity purified
|
|
Storage buffer
|
Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 10mM PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
|
|
Form
|
Liquid
|
|
Concentration
|
0.200 mg/ml
|
|
Storage instructions
|
Store at +4°C.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD4 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
|
See below for CD4 antibody images, references, products related to ab24800 and other tools.
|
| |
CD4 antibody images:
|
 Western blot - CD4 antibody (ab24800)
CD4 antibody (ab24800) at 1 µg/ml + Heart (Human) Tissue Lysate - adult normal tissue (ab29431) at 10 µg/ml
Secondary
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Predicted band size : 59 kDa
Observed band size : 59 kDa
Additional bands at : 49 kDa,75 kDa. We are unsure as to the identity of these extra bands.
|
| |
| |
|
Search PubMed (MEDLINE) for references to CD4
|
| |
CD4 antibody - more information
|
Customer reviews (feedback) regarding CD4 antibody |
Customer FAQs regarding CD4 antibody |
Protocols for CD4 antibody |
Price and availability of products related to CD4 antibody |
| |
CD4 antibody - related products:
|
|
|
| |
CD4 antibody - other tools:
|
Contact Abcam with a Technical Enquiry about CD4 antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
