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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD4 antibody (ab61131)
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Product Name
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CD4 antibody
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See all CD4 antibodies (101)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to CD4
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Immunogen
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Synthetic non-phosphopeptide derived from human CD4 around the phosphorylation site of serine 433.
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Reacts with
(species key)
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Hu
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Specificity
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ab61131 detects endogenous levels of total CD4 protein.
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Tested applications
(see key)
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ELISA, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/5000.
IHC-P: 1/50 - 1/100.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human brain tissue.
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Cellular localization
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Cell membrane; Single pass type I membrane protein.
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Research areas
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Immunology >> Adaptive Immunity >> Regulatory T Cells
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Dendritic Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Immunology >> Adaptive Immunity >> T Cells >> CD
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Relevance
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CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Purification notes
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ab61131 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at -20°C. Stable for 12 months at -20°C
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD4 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CD4 antibody images, references, products related to ab61131 and other tools.
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CD4 antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD4 antibody (ab61131)
ab61131 at 1/50 dilution staining CD4 in human brain by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.
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Search PubMed (MEDLINE) for references to CD4
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CD4 antibody - more information
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Customer reviews (feedback) regarding CD4 antibody |
Customer FAQs regarding CD4 antibody |
Protocols for CD4 antibody |
Price and availability of products related to CD4 antibody |
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CD4 antibody - related products:
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CD4 antibody - other tools:
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Contact Abcam with a Technical Enquiry about CD4 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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