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- CD4 (phospho S433) antibody (ab61011)
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Product Name
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CD4 (phospho S433) antibody
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See all CD4 antibodies (101)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to CD4 (phospho S433)
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Immunogen
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Synthetic peptide from human CD4 around the phosphorylation site of serine 433 (R-M-SP-Q-I).
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Reacts with
(species key)
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Hu
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Specificity
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ab61011 detects endogenous levels of CD4 only when phosphorylated at serine 433.
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Tested applications
(see key)
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ELISA, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/40000.
IHC-P: 1/50 - 1/100.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human brain tissue
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Cellular localization
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Cell membrane; Single pass type I membrane protein.
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Research areas
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Immunology >> Adaptive Immunity >> Regulatory T Cells
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Dendritic Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Immunology >> Adaptive Immunity >> T Cells >> CD
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Relevance
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CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
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CD4 (phospho S433) antibody (ab61011) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Purification notes
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ab61011 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD4 (phospho S433) antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CD4 (phospho S433) antibody images, references, products related to ab61011 and other tools.
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CD4 (phospho S433) antibody images:
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 - CD4 (phospho S433) antibody (ab61011)
Immunohistochemical analysis of paraffin-embedded human brain tissue using ab61011 at a 1/50 dilution.
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Search PubMed (MEDLINE) for references to CD4
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CD4 (phospho S433) antibody - more information
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Customer reviews (feedback) regarding CD4 (phospho S433) antibody |
Customer FAQs regarding CD4 (phospho S433) antibody |
Protocols for CD4 (phospho S433) antibody |
Price and availability of products related to CD4 (phospho S433) antibody |
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CD4 (phospho S433) antibody - related products:
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CD4 (phospho S433) antibody - other tools:
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Contact Abcam with a Technical Enquiry about CD4 (phospho S433) antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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