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Anti-CD40 antibody [B-B20] (Biotin) (ab27283)

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Overview

  • Product nameAnti-CD40 antibody [B-B20] (Biotin)See all CD40 primary antibodies ...
  • Description
    Mouse monoclonal [B-B20] to CD40 (Biotin)
  • ConjugationBiotin
  • SpecificityThis antibody is specific for CD40.
  • Tested applicationsFlow Cyt more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Raji cell line

Properties

Applications

Our Abpromise guarantee covers the use of ab27283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Flow Cyt
  • Application notesFlow Cyt: Use 10 µl to label 106 cells or 100 µl of whole blood .

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionReceptor for TNFSF5/CD40LG.
    • Tissue specificityB-cells and in primary carcinomas.
    • Involvement in diseaseDefects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
    • Sequence similaritiesContains 4 TNFR-Cys repeats.
    • Cellular localizationSecreted and Cell membrane.

      • Target information above from: UniProt accession P25942 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          AI326936 antibodyB cell associated molecule CD40 antibodyB cell surface antigen CD40 antibody
          B cell-associated molecule antibodyB-cell surface antigen CD40 antibodyBp50 antibodyCD 40 antibodyCD40 antibodyCD40 antibodyCD40 antigen (TNF receptor superfamily member 5) antibodyCD40 antigen antibodyCD40 molecule antibodyCD40 molecule, TNF receptor superfamily member 5 antibodyCD40 protein antibodyCD40 type II isoform antibodyCD40L receptor antibodyCDw40 antibodyGP39 antibodyHIGM1 antibodyIGM antibodyIMD3 antibodyMGC9013 antibodyNerve growth factor receptor related B lymphocyte activation molecule antibodyOTTHUMP00000031699 antibodyOTTHUMP00000031700 antibodyp50 antibodyT-BAM antibodyTBAM antibodyTNF receptor superfamily member 5 antibodyTNFRSF5 antibodyTNFRSF5 antibodyTNR5_HUMAN antibodyTRAP antibodyTumor necrosis factor receptor superfamily , member 5 antibodyTumor necrosis factor receptor superfamily member 5 antibodyTumor necrosis factor receptor superfamily member 5 precursor antibodyTumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody
        see all

      Anti-CD40 antibody [B-B20] (Biotin) images

      • Flow Cytometry / FACS - CD40 antibody [B-B20] (Biotin) (ab27283)
        Flow Cytometry / FACS - CD40 antibody [B-B20] (Biotin) (ab27283)
        A typical staining pattern with ab27283.

      References for Anti-CD40 antibody [B-B20] (Biotin) (ab27283)

      ab27283 has not yet been referenced specifically in any publications.

      Publishing research using ab27283 ? Please let us know so that we can cite the reference in this datasheet

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