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Anti-CD40 antibody [MAB89] (ab19684)

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This product is covered by the Abpromise guarantee. Our scientific support team are available to answer any questions or queries - fill out an inquiry form for ab19684 for help.

Alternatively, you can search the previous enquiries about this product to see if your query has already been answered.

2 questions for ab19684

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Question 1

Tuesday 29-August-2006

Was ab19684 characterized for the cellular activation of white blood cells and dendrites specifically?

ANSWER:

 

Thank you for your enquiry.

The "activation" information came from the following published reference. The paper discusses activation of B cells.

http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=48559&blobtype=pdf

I have also added a link to the PubMed entry for this article on the datasheet for future reference.

I hope this information helps. Please do not hesitate to contact us again if you have anything further.

Question 2

Thursday 04-May-2006

Please find out what was done to validate that this antibody clone is actually directed against CD40 (immunoabsorption, etc.).

ANSWER:

 

Thank you for your enquiry.

Mouse monoclonal [MAB89] to CD40 (ab19684) was characterized as part of the Leucocyte Workshop VI. Testing was done by IHC (frozen sections), Western blot, and functional studies.

There are several published references listed on the datasheet for this antibody. The following reference discusses the original characterization of this clone.

Vall A et al. Activation of human B lymphocytes through CD40 and interleukin 4. Eur J Immunol 19:1463-7 (1989). PubMed: 2476318

I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

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