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Product Name
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CD44 antibody [F10-44-2]
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See all CD44 antibodies (59)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [F10-44-2] to CD44
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Immunogen
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CD44-positive cell preparation.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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Flow Cyt, IHC-Fr, IHC-P, IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use 0.5-1µg for 106 cells.
IHC-P: Use at a concentration of 0.5 - 2 µg/ml. Antigen retrieval is not essential but may optimise staining.
IHC-Fr: Use at a concentration of 0.5 - 2 µg/ml.
IP: Use at a concentration of 0.5 - 2 µg/ml.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Type I membrane protein.
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Research areas
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Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Neutrophil Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Dendritic Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Cancer >> Tumor biomarkers >> Other
Cancer >> Tumor immunology >> CD markers
Stem Cells >> Mesenchymal Stem Cells >> Surface Molecules
Immunology >> Cell Type Markers >> CD >> Adhesion
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Relevance
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CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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F10-44-2
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Isotype
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IgG2a
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS (pH 7.4) Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD44 antibody [F10-44-2] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for CD44 antibody [F10-44-2] (ab6124)
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This product has been used in: (two most recent references)
Hunt ME & Brown DR Role of sialidase in Mycoplasma alligatoris-induced pulmonary fibroblast apoptosis. Vet Microbiol 121:73-82 (2007). PubMed: 17276629
Hunt ME & Brown DR Mycoplasma alligatoris infection promotes CD95 (FasR) expression and apoptosis of primary cardiac fibroblasts. Clin Diagn Lab Immunol 12:1370-7 (2005). PubMed: 16339059
If you publish research using ab6124 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CD44
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CD44 antibody [F10-44-2] - more information
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Customer reviews (feedback) regarding CD44 antibody [F10-44-2] |
Customer FAQs regarding CD44 antibody [F10-44-2] |
Protocols for CD44 antibody [F10-44-2] |
Price and availability of products related to CD44 antibody [F10-44-2] |
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CD44 antibody [F10-44-2] - related products:
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CD44 antibody [F10-44-2] - other tools:
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Contact Abcam with a Technical Enquiry about CD44 antibody [F10-44-2] |
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