CD44 antibody (ab24504)

Product Name 

CD44 antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to CD44

Immunogen 

Synthetic peptide surrounding amino acid 39 (Human)

Reacts with 
(species key)

Hu, Ms, Rat

Tested applications 
(see key)

IHC-Fr, IP, WB

Abreviews 

Customer reviews (see key)

Read about Abreviews (Read all Abreviews)

Application notes 
(see key)

Recommended dilutions
IHC-Fr: Use at a concentration of 20 µg/ml.
IP: Use at a concentration of 20 µg/ml.
WB: Use at a concentration of 1-4 µg/ml. Predicted molecular weight: 82 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

HeLa cell extract

Cellular localization 

Type I membrane protein.

Research areas 

Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Neutrophil Lineage
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Dendritic Cell Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Cancer >> Tumor biomarkers >> Other
Cancer >> Tumor immunology >> CD markers
Stem Cells >> Mesenchymal Stem Cells >> Surface Molecules
Immunology >> Cell Type Markers >> CD >> Adhesion

Relevance 

CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.

Database links 

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 50% Glycerol, 1.0% BSA, PBS

Material safety datasheet (MSDS) for this product:
Glycerol MSDS

Form 

Liquid

Concentration 

0.200 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

See below for CD44 antibody images, references, products related to ab24504 and other tools.

CD44 antibody images:

References for CD44 antibody (ab24504)

  This product has been used in:

Garcia GG et al. Age-related defects in moesin/ezrin cytoskeletal signals in mouse CD4 T cells. J Immunol 179:6403-9 (2007). WB, IP; Mouse. PubMed: 17982027

If you publish research using ab24504 please let us know so that we can cite the reference on this datasheet.

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