CD45 peptide (ab17550)
Our Abpromise guarantee covers the use of ab17550 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Blocking||BL: Use a concentration of 1 µg/ml.|
- B220CD 45CD45
- CD45 antigenCD45RGP180L CAL-CALCALeukocyte common antigenlocLy-5LY5Lyt-4OTTHUMP00000033813OTTHUMP00000033816OTTHUMP00000033817OTTHUMP00000038574Protein tyrosine phosphatase receptor type CProtein tyrosine phosphatase receptor type c polypeptideprotein tyrosine phosphatase, receptor type, CPTPRCPTPRC_HUMANReceptor-type tyrosine-protein phosphatase CSCID due to PTPRC deficiencyT200T200 glycoproteinT200 leukocyte common antigen
Genetic variations in PTPRC are involved in multiple sclerosis susceptibility (MS) [MIM:126200]. MS is a neurodegenerative disorder characterized by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in third or fourth decade with intermittent progression over an extended period. The cause is still uncertain.
Contains 2 fibronectin type-III domains.
Contains 2 tyrosine-protein phosphatase domains.
modificationsHeavily N- and O-glycosylated.
CD45 peptide images
ab10559 rabbit polyclonal to CD45 (1/500) with secondary goat anti-rabbit IgG ab6721 (1/5000).
Expected molecular weight: 147 kDa. WB exposure time: 1min 30sec
Lanes 1 to 10: 20
g of cell lysate per lane µ
Lanes 6 to 10: ab17550 CD45 blocking peptide used at 1
Lane 1: HeLa Nuclear Extract (ab10559)
Lane 2: HeLa Whole Cell Lysate (ab10559)
Lane 3: A431 Whole Cell Lysate (ab10559)
Lane 4: Jurkat Whole Cell Lysate (ab10559)
Lane 5: HEK293 Whole Cell Lysate (ab10559)
Lane 6: HeLa Nuclear Extract (ab10559+ ab17550)
Lane 7: HeLa Whole Cell Lysate (ab10559+ ab17550)
Lane 8: A431 Whole Cell Lysate (ab10559+ ab17550)
Lane 9: Jurkat Whole Cell Lysate (ab10559+ ab17550)
Lane 10: HEK293 Whole Cell Lysate (ab10559+ ab17550)
Binding of ab10559 to Jurkat cell lysate was blocked using ab17550.
References for CD45 peptide (ab17550)
ab17550 has not yet been referenced specifically in any publications.