![Flow Cytometry / FACS - CD45RC antibody [MRC OX-22] (Biotin) (ab33937) image](#ab33937_FACS_1.jpg)
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Products:Immunology >> Adaptive Immunity >> B Cells >> CD
Overview
Product name
Anti-CD45RC antibody [MRC OX-22] (Biotin)
See all CD45RC products (16) ...
Description
Mouse monoclonal [MRC OX-22] to CD45RC (Biotin)
Conjugation
Biotin
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Rat
Immunogen
PHA stimulated rat lymphocytes
Positive control
rat splenocytes.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: 1% BSA
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
MRC OX-22
Myeloma
NS1
Isotype
IgG1
Research areas
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Signal Transduction >> Protein Phosphorylation >> Tyrosine Phosphatases
Immunology >> Cell Type Markers >> CD >> Non-lineage
Immunology >> Adaptive Immunity >> T Cells >> CD
Immunology >> Adaptive Immunity >> B Cells >> CD
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Flow Cytometry / FACS - CD45RC antibody [MRC OX-22] (Biotin) (ab33937)
![Flow Cytometry / FACS - CD45RC antibody [MRC OX-22] (Biotin) (ab33937) image](/ps/datasheet/Images/33/ab33937/ab33937_FACS_1.jpg)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab33937 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
Flow Cyt
Application notes
Flow Cyt: Use neat. Use 10µl of the suggested working dilution to label 106 cells in 100µl.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.
Cellular localization
Membrane; Single-pass type I membrane protein. Membrane raft. Note: Colocalized with DPP4 in membrane rafts.
Alternative names
- B220 antibody
- CD45 antibody
- CD45R antibody
see all
Database links
Anti-CD45RC antibody [MRC OX-22] (Biotin) images:
Flow Cytometry / FACS - CD45RC antibody [MRC OX-22] (Biotin) (ab33937)
Staining of rat splenocytes with ab33937
References for Anti-CD45RC antibody [MRC OX-22] (Biotin) (ab33937)
ab33937 has not yet been referenced specifically in any publications.
Publishing research using ab33937? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"