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Anti-CD5 antibody [4C7] (ab851)

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Overview

Product name

Anti-CD5 antibody [4C7]
See all CD5 products (60) ...

Description

Mouse monoclonal [4C7] to CD5

Tested applications

IHC-Fr, IHC-Pmore details

Cross reactivity

Reacts with

Human

Positive control

Mantle cell lymphoma

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: PBS, Carrier protein, Van Gogh Yellow Diluent, pH 7.3

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

4C7

Myeloma

unknown

Isotype

IgG1

Light chain type

kappa

Research areas

Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Immunology >> Adaptive Immunity >> T Cells >> CD
Immunology >> Adaptive Immunity >> B Cells >> CD

Applications

Show applications key

Our Abpromise guarantee covers the use of ab851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • IHC-Fr

     

  • IHC-P

     

Application notes

This antibody may be diluted to a titer of 1:50-1:100 in an ABC method.
We suggest an incubation period of 30-60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation and dilutions should be determined by the user.
Heat mediated antigen retrieval of formalin fixed paraffin embedded tissues may be required before immunostaining.

Target

Function

May act as a receptor in regulating T-cell proliferation. CD5 interacts with CD72/LYB-2.

Sequence similarities

Contains 3 SRCR domains.

Cellular localization

Membrane.

Target information above from: UniProt accessionP06127 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • CD 5 antibody
  • CD5 antibody
  • CD5 antibody
  • CD5 antigen (p56 62) antibody
  • CD5 antigen antibody
  • CD5 molecule antibody
  • CD5_HUMAN antibody
  • LEU 1 antibody
  • LEU1 antibody
  • Ly12 antibody
  • LyA antibody
  • Lymphocyte Antigen CD5 antibody
  • Lymphocyte antigen T1/Leu 1 antibody
  • Lymphocyte antigen T1/Leu-1 antibody
  • Lymphocyte glycoprotein T1/Leu1 antibody
  • OTTHUMP00000236973 antibody
  • p56 62 antibody
  • T cell surface glycoprotein CD5 antibody
  • T-cell surface glycoprotein CD5 antibody
  • T1 antibody
see all

Database links

References for Anti-CD5 antibody [4C7] (ab851)

This product has been referenced in:

  • Tateyama Het al. Immunoreactivity of a new CD5 antibody with normal epithelium and malignant tumors including thymic carcinoma. Am J Clin Pathol 111:235-40 (1999).Read more (PubMed: 9930146) »
  • Kaufmann Oet al. Immunohistochemical detection of CD5 with monoclonal antibody 4C7 on paraffin sections. Am J Clin Pathol 108:669-73 (1997).Read more (PubMed: 9384449) »

See all 2 publications for this product

Publishing research using ab851? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"