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Anti-CD51 + CD61 antibody [23C6] (Phycoerythrin) (ab33078)

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This product is covered by the Abpromise guarantee. Our scientific support team are available to answer any questions or queries - fill out an inquiry form for ab33078 for help.

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1 question for ab33078

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Question 1

Thursday 23-August-2007

Do you know if this antibody works only for osteoclastomas - or can MCSF/RankL cultured osteoclast also be stained/sorted with this antibody? Thanks,

ANSWER:

  

Thank you for your enquiry.

I can confirm that this product recognises the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. 23C6 reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"