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Product name
Anti-CD62E antibody [1.2B6] (FITC)
See all CD62E products (18) ...
Description
Mouse monoclonal [1.2B6] to CD62E (FITC)
Conjugation
FITC
Tested applications
IHC-Fr, ELISA, Flow Cytmore details
Cross reactivity
Reacts with
Human, Pig
Immunogen
TNF-activated human umbilical vein endothelial cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C in the dark. Do not freeze.
Storage buffer
Preservative: 10mM Sodium Azide
Constituents: PBS, 1mg/ml BSA
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Monoclonal
Clone number
1.2B6
Isotype
IgG1
Research areas
Cardiovascular >> Cardiovascular Markers >> Cell Markers >> Endothelial Cells
Stem Cells >> Endothelial Progenitors >> Endothelial Markers
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Leukocyte recruitment >> Cell adhesion molecules
Immunology >> Cell Type Markers >> CD >> Adhesion
Applications
Show applications key
Our Abpromise guarantee covers the use of ab77888 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr
ELISA
Flow Cyt
Application notes
IHC-Fr: Use at an assay dependent dilution.
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use 10µL of conjugate per test.
Studies in a wide range of cell interactions in the vasculature together with diagnostic implications and also inhibits cellular adhesion.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
Sequence similarities
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains.
Cellular localization
Membrane.
Target information above from: UniProt accessionP16581
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- E selectin antibody
- Leukocyte endothelial cell adhesion molecule 2 antibody
- CD 62E antibody
see all
Database links
- Entrez Gene: 6401 Human
- Entrez Gene: 397508 Pig
- Omim: 131210 Human
- SwissProt: P16581 Human
- Unigene: 82848 Human
References for Anti-CD62E antibody [1.2B6] (FITC) (ab77888)
ab77888 has not yet been referenced specifically in any publications.
Publishing research using ab77888? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"