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- Secondary antibodies
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Product name
Anti-CD62E antibody [CL2/6] (Biotin)
See all CD62E products (18) ...
Description
Mouse monoclonal [CL2/6] to CD62E (Biotin)
Conjugation
Biotin
Specificity
This antibody is specific for CD62E.
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Dog, Human
Immunogen
The details of the immunogen for this antibody are not available.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, Tris buffered saline
Concentration
Concentration information loading...
Purification notes
ab33274 is a purified IgG.
Clonality
Monoclonal
Clone number
CL2/6
Isotype
IgG2a
Research areas
Cardiovascular >> Cardiovascular Markers >> Cell Markers >> Endothelial Cells
Stem Cells >> Endothelial Progenitors >> Endothelial Markers
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Leukocyte recruitment >> Cell adhesion molecules
Immunology >> Cell Type Markers >> CD >> Adhesion
Applications
Show applications key
Our Abpromise guarantee covers the use of ab33274 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt
Application notes
Flow Cyt: Use 10µl for 106 cells in 100µl.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
Sequence similarities
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains.
Cellular localization
Membrane.
Target information above from: UniProt accessionP16581
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- E selectin antibody
- CD 62E antibody
- CD26E antibody
see all
Database links
- Entrez Gene: 403999 Dog
- Entrez Gene: 6401 Human
- Omim: 131210 Human
- SwissProt: P33730 Dog
- SwissProt: P16581 Human
- Unigene: 82848 Human
References for Anti-CD62E antibody [CL2/6] (Biotin) (ab33274)
This product has been referenced in:
- Scotland RS et al. C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression. Proc Natl Acad Sci U S A 102:14452-7 (2005).Read more (PubMed: 16179391) »
- Kukreti S et al. Molecular mechanisms of monocyte adhesion to interleukin-1beta-stimulated endothelial cells under physiologic flow conditions. Blood 89:4104-11 (1997).Read more (PubMed: 9166852) »
See all 2 publications for this product
Publishing research using ab33274? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"