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Anti-CD62E antibody [UZ7] (ab22631)

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Overview

Product name

Anti-CD62E antibody [UZ7]
See all CD62E products (18) ...

Description

Rat monoclonal [UZ7] to CD62E

Tested applications

IHC-Fr, WB, ELISA, IP, ICC/IF, Flow Cytmore details

Cross reactivity

Reacts with

Mouse

Immunogen

Tissue / cell preparation (Mouse; LPS-activated mlEND1 cells expressing E-selectin at their cell surface).

Epitope

This antibody recognizes a conformational epitope in the CR1 region in murine E-selectin.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Protein A purified

Primary antibody notes

This antibody partially inhibits leukocyte adhesion to murine activated endothelial cells.

Clonality

Monoclonal

Clone number

UZ7

Myeloma

Sp2/0

Isotype

IgG2a

Research areas

Cardiovascular >> Cardiovascular Markers >> Cell Markers >> Endothelial Cells
Stem Cells >> Endothelial Progenitors >> Endothelial Markers
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Leukocyte recruitment >> Cell adhesion molecules
Immunology >> Cell Type Markers >> CD >> Adhesion

Applications

Show applications key

Our Abpromise guarantee covers the use of ab22631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.

Sequence similarities

Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains.

Cellular localization

Membrane.

Target information above from: UniProt accessionP16581 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • E selectin antibody
  • CD 62E antibody
  • CD26E antibody
  • CD62 antigen-like family member E antibody
  • CD62E antibody
  • CD62E antigen antibody
  • E selectin antibody
  • E-selectin antibody
  • ELAM 1 antibody
  • ELAM antibody
  • ELAM-1 antibody
  • ELAM1 antibody
  • Endothelial adhesion molecule 1 antibody
  • Endothelial leukocyte adhesion molecule 1 antibody
  • ESEL antibody
  • LECAM 2 antibody
  • LECAM2 antibody
  • Leukocyte endothelial cell adhesion molecule 2 antibody
  • Leukocyte-endothelial cell adhesion molecule 2 antibody
  • LYAM2_HUMAN antibody
  • SELE antibody
  • Selectin E antibody
  • SelectinE antibody
see all

Database links

References for Anti-CD62E antibody [UZ7] (ab22631)

ab22631 has not yet been referenced specifically in any publications.

Publishing research using ab22631? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"