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Overview

  • Product nameCD70 proteinSee all CD70 proteins and peptides ...
  • Protein descriptionRecombinant fragment of Human CD70 extracellular domain (amino acids 39-193) fused to an N-terminal His Tag (Swiss Prot P32970).
  • Uniprot accessionP32970
  • Protein length155 amino acids
  • Expression hostCHO

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesPurity: Greater than 95% by SDS-PAGE gel and HPLC analyses
  • FormLyophilised
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 3.00
    Constituent: 0.6% Sodium citrate
  • Concentration information loading...
  • Sequence notesHHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab119815 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    HPLC HPLC: Use at an assay dependent dilution.
    Functional Studies FuncS: Use at an assay dependent concentration.

    Protein info

    • Alternative names
        CD 27LCD 70CD27 L
        CD27 LGCD27 ligandCD27-LCD27LCD27LGCD70CD70 antigenCD70 moleculeCD70_HUMANKi 24 antigenKi24 antigenSurface antigen CD70TNFSF 7TNFSF7Tumor necrosis factor ligand superfamily member 7
      see all
  • FunctionCytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
  • Sequence similaritiesBelongs to the tumor necrosis factor family.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P32970 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for CD70 protein (ab119815)

    ab119815 has not yet been referenced specifically in any publications.

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