Anti-CD80 antibody [1G10] (Biotin) (ab24970)

Overview

  • Product nameAnti-CD80 antibody [1G10] (Biotin)
    See all CD80 primary antibodies
  • Description
    Rat monoclonal [1G10] to CD80 (Biotin)
  • ConjugationBiotin
  • Specificityab24970 recognises mouse CD80 (B7-1).
  • Tested applicationsFlow Cyt, IP, Blockingmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes


    The monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80, but it does not block stimulation of T cells by natural antigen-presenting cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab24970 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IP
Blocking
  • Application notesBL:(In vivo and in vitro blocking of ligand binding): Use at an assay dependent dilution.
    Flow Cyt: Use 1µg for 106 cells.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
    • Tissue specificityExpressed on activated B-cells, macrophages and dendritic cells.
    • Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Activation B7 1 antigen antibody
      • Activation B7-1 antigen antibody
      • Activation B71 antigen antibody
      • B lymphocyte activation antigen B7 antibody
      • B7 antibody
      • B7-1 antibody
      • B7-1 antigen antibody
      • BB1 antibody
      • CD 80 antibody
      • CD28 antigen ligand 1 antibody
      • CD28 antigen ligand 1 B71 antigen antibody
      • CD28 antigen ligand 1 B71 antigen antibody
      • CD28LG antibody
      • CD28LG1 antibody
      • CD28LG1 antibody
      • CD80 antibody
      • CD80 antibody
      • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody
      • CD80 antigen antibody
      • CD80 antigen precursor antibody
      • CD80 molecule antibody
      • CD80_HUMAN antibody
      • Costimulatory factor CD80 antibody
      • costimulatory molecule variant IgV-CD80 antibody
      • CTLA 4 counter receptor B7.1 antibody
      • CTLA-4 counter-receptor B7.1 antibody
      • LAB 7 antibody
      • LAB7 antibody
      • LAB7 antibody
      • T lymphocyte activation antigen CD80 antibody
      • T-lymphocyte activation antigen CD80 antibody
      see all

    References for Anti-CD80 antibody [1G10] (Biotin) (ab24970)

    ab24970 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab24970.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"