Overview
- Product nameAnti-CD80 antibody [1G10] (Biotin)See all CD80 primary antibodies ...
- DescriptionRat monoclonal [1G10] to CD80 (Biotin)
- ConjugationBiotin
- Specificityab24970 recognises mouse CD80 (B7-1).
- Tested applicationsFlow Cyt, IP, Blocking more details
- Species reactivityReacts with: Mouse
- Immunogen
The details of the immunogen for this antibody are not available.
Properties
- FormLiquid
- Storage instructionsStore at +4°C.
- Storage bufferPreservative: 0.1% Sodium Azide
Constituents: PBS -
Concentration information loading... - PurityIgG fraction
- Primary antibody notes The monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80, but it does not block stimulation of T cells by natural antigen-presenting cells.
- Clonality Monoclonal
- Clone number1G10
- IsotypeIgG2a
- Light chain typekappa
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab24970 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| Flow Cyt | |
| IP | |
| Blocking |
Flow Cyt: Use 1µg for 106 cells.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionInvolved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
- Tissue specificityExpressed on activated B-cells, macrophages and dendritic cells.
- Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. - Cellular localizationMembrane.
-
Database links
- Entrez Gene: 12519 Mouse
- SwissProt: Q00609 Mouse
- Unigene: 89474 Mouse
Target information above from: UniProt accession
P33681
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Activation B7 1 antigen antibodyActivation B7-1 antigen antibodyActivation B71 antigen antibody
- B lymphocyte activation antigen B7 antibodyB7 antibodyBB1 antibodyCD 80 antibodyCD28 antigen ligand 1 B71 antigen antibodyCD28 antigen ligand 1 B71 antigen antibodyCD28LG antibodyCD28LG1 antibodyCD28LG1 antibodyCD80 antibodyCD80 antibodyCD80 antigen antibodyCD80 antigen precursor antibodyCD80 molecule antibodyCD80_HUMAN antibodyCostimulatory factor CD80 antibodyCTLA 4 counter receptor B7.1 antibodyCTLA-4 counter-receptor B7.1 antibodyLAB 7 antibodyLAB7 antibodyLAB7 antibodyT lymphocyte activation antigen CD80 antibodyT-lymphocyte activation antigen CD80 antibody
see all
References for Anti-CD80 antibody [1G10] (Biotin) (ab24970)
ab24970 has not yet been referenced specifically in any publications.