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Overview

  • Product nameAnti-CD80 antibody [MEM-233] (PerCP)See all CD80 primary antibodies ...
  • Description
    Mouse monoclonal [MEM-233] to CD80 (PerCP)
  • ConjugationPerCP
  • Specificityab82410 reacts with CD80 expressed on professional antigen presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
  • Tested applicationsFlow Cyt more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Extracellular domain of human CD80 fused to human IgG1(Fc)

  • Positive controlRAJI Human Burkitt lymphoma cell line.

Properties

Applications

Our Abpromise guarantee covers the use of ab82410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Flow Cyt Flow Cyt: Use 10µl for 106 cells. or 100 µl of whole blood.

Target

  • FunctionInvolved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
  • Tissue specificityExpressed on activated B-cells, macrophages and dendritic cells.
  • Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P33681 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Activation B7-1 antigen antibodyB lymphocyte activation antigen B7 antibodyB7 antibody
        BB1 antibodyCD28LG antibodyCD28LG1 antibodyCD80 antibodyCD80 antibodyCD80 antigen antibodyCD80 molecule antibodyCD80_HUMAN antibodyCostimulatory factor CD80 antibodyCTLA-4 counter-receptor B7.1 antibodyLAB7 antibodyT-lymphocyte activation antigen CD80 antibody
      see all

    References for Anti-CD80 antibody [MEM-233] (PerCP) (ab82410)

    This product has been referenced in:
    • Campioni D  et al. Immunophenotypic heterogeneity of bone marrow-derived mesenchymal stromal cells from patients with hematologic disorders: correlation with bone marrow microenvironment. Haematologica 91:364-8 (2006). Flow Cyt ; Human . Read more (PubMed: 16531259) »

    See 1 Publication for this product

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