Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab62636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
Flow Cyt
  • Application notesFlow Cyt: 1/10 - 1/50. Use 10µl to label 1x106 cells in 100µl.
    IHC-Fr: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
    • Tissue specificityExpressed on activated B-cells, macrophages and dendritic cells.
    • Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Activation B7 1 antigen antibody
      • Activation B7-1 antigen antibody
      • Activation B71 antigen antibody
      • B lymphocyte activation antigen B7 antibody
      • B7 antibody
      • B7-1 antibody
      • B7-1 antigen antibody
      • BB1 antibody
      • CD 80 antibody
      • CD28 antigen ligand 1 antibody
      • CD28 antigen ligand 1 B7 1 antigen antibody
      • CD28 antigen ligand 1 B71 antigen antibody
      • CD28LG antibody
      • CD28LG1 antibody
      • CD80 antibody
      • CD80 antibody
      • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody
      • CD80 antigen antibody
      • CD80 antigen precursor antibody
      • CD80 molecule antibody
      • CD80_HUMAN antibody
      • Costimulatory factor CD80 antibody
      • costimulatory molecule variant IgV-CD80 antibody
      • CTLA 4 counter receptor B7.1 antibody
      • CTLA-4 counter-receptor B7.1 antibody
      • LAB 7 antibody
      • LAB7 antibody
      • T lymphocyte activation antigen CD80 antibody
      • T-lymphocyte activation antigen CD80 antibody
      see all

    References for Anti-CD80 antibody [RM80] (ab62636)

    This product has been referenced in:
    • Ogawa S  et al. Opposing effects of anti-activation-inducible lymphocyte-immunomodulatory molecule/inducible costimulator antibody on the development of acute versus chronic graft-versus-host disease. J Immunol 167:5741-8 (2001). Read more (PubMed: 11698447) »

    See 1 Publication for this product

    Product Wall

    Thank you for contacting us. I have had an opportunity to review our catalog and have found four products that may fulfill your needs. Each will react with mouse. Three have been produced in rat (ab62636, ab25208, ab40981)so cross reactivity will not b...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"