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Product Name
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CD9 antibody [ALB 6]
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See all CD9 antibodies (22)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [ALB 6] to CD9
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Immunogen
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Human bone marrow malignant cells from acute non-T, non-B leukemia.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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Flow Cyt, IHC-Fr
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use 2µg for 5X105 cells/test.
IHC-Fr (or cell smears): 1/25 - 1/50.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Integral membrane protein.
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Research areas
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Developmental Biology >> Embryogenesis >> Embryonic stem cells >> Intracellular
Developmental Biology >> Reproduction >> Fertilisation
Stem Cells >> Embryonic Stem Cells >> Surface Molecules
Immunology >> Cell Type Markers >> CD >> Platelets
Cardiovascular >> Blood >> Other
Cardiovascular >> Blood >> Platelets
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Relevance
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CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
ab19715 recognizes blood platelets and a few granulocytic cells of normal bone marrow. Recognizes the distal convoluted tubule and the distal right tubule of nephrons.
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CD9 antibody [ALB 6] (ab19715) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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ALB 6
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Myeloma
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NS1/1-Ag4-1
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: The addition of 0.1% (w/v) sodium azide is recommended for storage up to one month at 2-8° C.
Constituents: PBS, 1mg/ml BSA
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Form
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Liquid
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Concentration
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0.200 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD9 antibody [ALB 6] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for CD9 antibody [ALB 6] (ab19715)
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This product has been used in:
Singethan K et al. CD9 clustering and formation of microvilli zippers between contacting cells regulates virus-induced cell fusion. Traffic 9:924-35 (2008). PubMed: 18363777
If you publish research using ab19715 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CD9
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CD9 antibody [ALB 6] - more information
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