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Product Name
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CD9 antibody [MM2/57]
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See all CD9 antibodies (22)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [MM2/57] to CD9
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Immunogen
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Full length protein (Human).
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Reacts with
(species key)
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Ms, Rb
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Tested applications
(see key)
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FuncS, IHC-Fr, IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
FuncS: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Detects a band of approximately 25 kDa. Dilution optimised using Chromogenic detection.
Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Platelets and Fibroblasts (Rabbit).
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Cellular localization
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Integral membrane protein.
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Research areas
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Developmental Biology >> Embryogenesis >> Embryonic stem cells >> Intracellular
Developmental Biology >> Reproduction >> Fertilisation
Stem Cells >> Embryonic Stem Cells >> Surface Molecules
Immunology >> Cell Type Markers >> CD >> Platelets
Cardiovascular >> Blood >> Other
Cardiovascular >> Blood >> Platelets
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Relevance
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CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
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CD9 antibody [MM2/57] (ab19761) |
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 12527 (Mouse)
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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MM2/57
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Myeloma
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NS1
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Isotype
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IgG2b
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS, 1mg/ml BSA. pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD9 antibody [MM2/57] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for CD9 antibody [MM2/57] (ab19761)
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This product has been used in:
Singethan K et al. CD9 clustering and formation of microvilli zippers between contacting cells regulates virus-induced cell fusion. Traffic 9:924-35 (2008). PubMed: 18363777
If you publish research using ab19761 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CD9
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CD9 antibody [MM2/57] - more information
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