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Product Name 

CD9 antibody [MM2/57]

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal [MM2/57] to CD9

Immunogen 

Full length protein (Human).

Reacts with 
(species key)

Ms, Rb

Tested applications 
(see key)

FuncS, IHC-Fr, IP, WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
FuncS: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Detects a band of approximately 25 kDa. Dilution optimised using Chromogenic detection.
Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Platelets and Fibroblasts (Rabbit).

Cellular localization 

Integral membrane protein.

Research areas 

Developmental Biology >> Embryogenesis >> Embryonic stem cells >> Intracellular
Developmental Biology >> Reproduction >> Fertilisation
Stem Cells >> Embryonic Stem Cells >> Surface Molecules
Immunology >> Cell Type Markers >> CD >> Platelets
Cardiovascular >> Blood >> Other
Cardiovascular >> Blood >> Platelets

Relevance 

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.

 

CD9 antibody [MM2/57] (ab19761)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

12527    (Mouse)

SwissProt

    

P40240    (Mouse)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

MM2/57

Myeloma 

NS1

Isotype 

IgG2b

Purity 

Protein A purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, 1mg/ml BSA. pH 7.2

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.100 mg/ml

Storage instructions 

Store at +4°C.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD9 antibody [MM2/57] is on this datasheet. But please do contact us if you would like any reassurance!



References for CD9 antibody [MM2/57] (ab19761)

Specific publication references   This product has been used in:

Singethan K et al. CD9 clustering and formation of microvilli zippers between contacting cells regulates virus-induced cell fusion. Traffic 9:924-35 (2008). PubMed: 18363777

If you publish research using ab19761 please let us know so that we can cite the reference on this datasheet.

 

Search PubMed (MEDLINE) for references to CD9

 

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