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Anti-CEACAM1 antibody [29H2] (ab49510)

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Overview

Product name

Anti-CEACAM1 antibody [29H2]
See all CEACAM1 products (7) ...

Description

Mouse monoclonal [29H2] to CEACAM1

Specificity

ab49510 recognises human CD66a antigen, also known as biliary glycoprotein (BGP).

Tested applications

IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Prokaryotic recombinant protein corresponding to a 170 amino acid truncate (266 to 436aa) of the CD66a molecule.

Positive control

Immunohistochemistry - Liver.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

29H2

Myeloma

P3-NS1/1-Ag4-1

Isotype

IgG1

Light chain type

kappa

Research areas

Tags & Cell Markers >> Cell Type Markers >> Tumor Associated

  • Immunohistochemistry (Paraffin-embedded sections) - CEACAM1 antibody [29H2] (ab49510)Immunohistochemistry (Paraffin-embedded sections) - CEACAM1 antibody [29H2] (ab49510) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab49510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    IHC-P

      See more...Read more →

    IHC-P: 1/50 - 1/100. 1/50 - 1/100. High temperature antigen unmasking technique. 60 minutes primary antibody incubation at 25oC.

Application notes

Is unsuitable for ,IHC-Fr or WB.

Target

Sequence similarities

Belongs to the immunoglobulin superfamily. CEA family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Cellular localization

Secreted; Cell membrane and Cell membrane. Localizes to sites of cell-cell contact.

Target information above from: UniProt accessionP13688 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Form

There are 11 isoforms produced by alternative splicing. Isoform 1 = BGPa; CEACAM1-4L; TM1-CEA; Isoform 2 = BGPg; CEACAM1-4C1; Isoform 3 = BGPh; CEACAM1-3; Isoform 4 = BGPi; CEACAM1-3C2; Isoform 5 = BGPy; CEACAM1-3AL; Isoform 6 = BGPb; CEACAM1-3L; TM2-CEA; Isoform 7 = BGPx; CEACAM1-1L; Isoform 8 = BGPc; CEACAM1-4S; TM3-CEA; Isoform 9 = BGPz; CEACAM1-3AS and Isoform 11 = BGPd; CEACAM1-3S.

Alternative names

  • CEACAM1 antibody
  • Antigen CD66 antibody
  • BGP 1 antibody
  • BGP antibody
  • BGP I antibody
  • BGP-1 antibody
  • BGP1 antibody
  • BGPI antibody
  • Biliary glycoprotein 1 antibody
  • Biliary glycoprotein adhesion molecule antibody
  • Biliary glycoprotein antibody
  • Carcinoembryonic antigen related cell adhesion molecule 1 antibody
  • Carcinoembryonic antigen-related cell adhesion molecule 1 antibody
  • CD66 antigen antibody
  • CD66a antibody
  • CD66a antigen antibody
  • CEACAM 1 antibody
  • CEACAM1 antibody
  • CEAM1_HUMAN antibody
  • meconium antigen 100 antibody
see all

Database links

Anti-CEACAM1 antibody [29H2] images:

  Immunohistochemistry (Paraffin-embedded sections) - CEACAM1 antibody [29H2] (ab49510)

Immunohistochemistry (Paraffin-embedded sections) - CEACAM1 antibody [29H2] (ab49510)

Immunohistochemical staining for CD66a antigen of normal human rectum using ab49510. Note apical membrane staining of absorptive epithelial cells. Paraffin section.

References for Anti-CEACAM1 antibody [29H2] (ab49510)

This product has been referenced in:

  • Lee W The CEACAM1 expression is decreased in the liver of severely obese patients with or without diabetes. Diagn Pathol 6:40 (2011).Read more (PubMed: 21569294) »
  • Gambichler T  et al. Protein expression of carcinoembryonic antigen cell adhesion molecules in benign and malignant melanocytic skin lesions. Am J Clin Pathol 131:782-7 (2009).Read more (PubMed: 19461083) »

See all 2 publications for this product

Publishing research using ab49510? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"