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Immunocytochemistry/ Immunofluorescence - CENPA antibody (ab62688)
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Product Name
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CENPA antibody
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See all CENPA antibodies (8)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to CENPA
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Immunogen
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Synthetic non-phosphopeptide derived from human CENPA around the phosphorylation site of serine 7 (R-R-SP-R-K).
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Reacts with
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Hu
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Specificity
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Detects endogenous levels of total CENPA protein.
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Tested applications
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ELISA, ICC/IF
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Abreviews
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Application notes
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Recommended dilutions
ELISA: 1/10000.
ICC/IF: 1/500 - 1/1000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Cell cycle >> Chromosome Structure >> Centromere
Chromatin and Nuclear Signaling >> Chromosome Structure >> Centromeres
Chromatin and Nuclear Signaling >> Histones >> Variants
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Relevance
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Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure, in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at -20°C. Stable for 12 months at -20°C
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CENPA antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CENPA antibody images, references, products related to ab62688 and other tools.
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CENPA antibody images:
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 Immunocytochemistry/ Immunofluorescence - CENPA antibody (ab62688)
ab62688 at 1/500 - 1/1000 dilution staining CENPA in HeLa cells (treated with Forskolin (40nM, 30mins) or untreated) by Immunofluorescence,
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Search PubMed (MEDLINE) for references to CENPA
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CENPA antibody - more information
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Customer reviews (feedback) regarding CENPA antibody |
Customer FAQs regarding CENPA antibody |
Protocols for CENPA antibody |
Price and availability of products related to CENPA antibody |
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CENPA antibody - related products:
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CENPA antibody - other tools:
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Contact Abcam with a Technical Enquiry about CENPA antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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