![Western blot - CETP antibody [ATM192] (ab2726) image](#ab2726-12226_copy.jpg)
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Products:Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cholesterol Metabolism
Overview
Product name
Anti-CETP antibody [ATM192]
See all CETP products (5) ...
Description
Mouse monoclonal [ATM192] to CETP
Specificity
Detects cholesteryl ester transfer protein (CETP) from human and rabbit tissues.
Tested applications
ELISA, IP, WBmore details
Cross reactivity
Reacts with
Rabbit, Human
Immunogen
Synthetic peptide: (131)CDSGRVRTDAPD(142) Immunizing peptide corresponds to the C-terminal amino acid residues 131-142 of the human CETP protein.
CDSGRVRTDA PD
Positive control
WB,IP: human serum WB: human liver lysate
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
PBS with 0.05% sodium azide
Concentration
Concentration information loading...
Purity
Protein A purified
Purification notes
Purified from ascites.
Clonality
Monoclonal
Clone number
ATM192
Isotype
IgG1
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Western blot - CETP antibody [ATM192] (ab2726)
![Western blot - CETP antibody [ATM192] (ab2726) image](/ps/datasheet/Images/2/ab2726/ab2726-12226_copy.jpg)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab2726 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution. (Use protein G beads.)
WB: 1/400Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa).
Target
Function
Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol.
Tissue specificity
Expressed by the liver and secreted in plasma.
Involvement in disease
Defects in CETP are a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
Defects in CETP are the cause of cholesteryl ester transfer protein deficiency (CETP deficiency) [MIM:607322]. This is an autosomal dominant condition associated with increased HDL cholesterol levels.
Sequence similarities
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Cellular localization
Secreted > extracellular space.
Target information above from: UniProt accessionP11597
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CETP antibody
- CETP_HUMAN antibody
- Cholesteryl ester transfer antibody
see all
Database links
- Entrez Gene: 1071 Human
- Omim: 118470 Human
- SwissProt: P11597 Human
- SwissProt: P22687 Rabbit
- Unigene: 89538 Human
Anti-CETP antibody [ATM192] images:
Western blot - CETP antibody [ATM192] (ab2726)
Anti-CETP antibody [ATM192] (ab2726) at 1/500 dilution + Whole cell lysate from rabbit fibroblasts at 40 µg
Secondary
HRP-conjugated rabbit anti-mouse at 1/2000 dilution
developed using the ECL technique
Performed under reducing conditions.
Predicted band size : 70 kDa
Exposure time : 2 minutes
This image is courtesy of an anonymous Abreview
References for Anti-CETP antibody [ATM192] (ab2726)
This product has been referenced in:
- Thomas APet al. Mouse monoclonal antipeptide antibodies specific for cholesteryl ester transfer protein (CETP). Hybridoma 15:359-64 (1996).Read more (PubMed: 8913785) »
See 1 publication for this product
Publishing research using ab2726? Please let us know so that we can cite the reference in this datasheet
![CETP antibody [ATM192] for WB in Rabbit (2726)](/ps/Reviews/Images/ab12226_66609.jpg)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"