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Western blot - CETP antibody (ab19012)
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Product Name
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CETP antibody
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See all CETP antibodies (5)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to CETP
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Immunogen
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Synthetic peptide corresponding to the C terminus of Human CETP.
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Reacts with
(species key)
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Hu, Ms, Rat, Rb
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Specificity
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This antibody recognises CETB (70 kDa).
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Tested applications
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution (PMID 19287187).
WB: Use at a concentration of 1 - 4 µg/ml. Predicted molecular weight: 70 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Atherosclerosis >> Lipid transport
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cholesterol Metabolism
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Relevance
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High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, 1% BSA, PBS Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CETP antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CETP antibody images, references, products related to ab19012 and other tools.
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CETP antibody images:
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 Western blot - CETP antibody (ab19012)
CETP antibody (ab19012)
Predicted band size : 70 kDa
Western blot analysis of CETP expresion in rabbit liver tissue lysate.
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References for CETP antibody (ab19012)
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This product has been used in:
Cho KH et al. Myocardial infarction patients show altered lipoprotein properties and functions when compared with stable angina pectoris patients. Exp Mol Med 41:67-76 (2009). ELISA; Human. PubMed: 19287187
If you publish research using ab19012 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CETP
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CETP antibody - more information
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Customer reviews (feedback) regarding CETP antibody |
Customer FAQs regarding CETP antibody |
Protocols for CETP antibody |
Price and availability of products related to CETP antibody |
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CETP antibody - related products:
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CETP antibody - other tools:
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Contact Abcam with a Technical Enquiry about CETP antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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