Anti-FOXN3 antibody [CHESC9H4] (ab50756)
Key features and details
- Mouse monoclonal [CHESC9H4] to FOXN3
- Suitable for: Dot blot, WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
Overview
-
Product name
Anti-FOXN3 antibody [CHESC9H4]
See all FOXN3 primary antibodies -
Description
Mouse monoclonal [CHESC9H4] to FOXN3 -
Host species
Mouse -
Tested applications
Suitable for: Dot blot, WBmore details -
Species reactivity
Reacts with: Recombinant fragment
Predicted to work with: Human -
Immunogen
Recombinant fragment corresponding to FOXN3.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. -
Storage buffer
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
-
Purity
Protein G purified -
Purification notes
Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a meium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Filtered through a 0.22 micrometer membrane. -
Clonality
Monoclonal -
Clone number
CHESC9H4 -
Isotype
IgG1 -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab50756 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Dot blot |
Use at an assay dependent concentration.
|
|
WB | (2) |
Use at an assay dependent concentration.
|
Notes |
---|
Dot blot
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
-
Function
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). -
Sequence similarities
Contains 1 fork-head DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
-
Database links
- Entrez Gene: 1112 Human
- Omim: 602628 Human
- SwissProt: O00409 Human
- Unigene: 434286 Human
- Unigene: 621371 Human
-
Alternative names
- C14orf116 antibody
- Checkpoint suppressor 1 antibody
- CHES1 antibody
see all
Datasheets and documents
-
Datasheet download
References (3)
ab50756 has been referenced in 3 publications.
- Xue W et al. FOXN3 is downregulated in osteosarcoma and transcriptionally regulates SIRT6, and suppresses migration and invasion in osteosarcoma. Oncol Rep 41:1404-1414 (2019). PubMed: 30483801
- Sun J et al. The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells. Oncotarget 7:43534-43545 (2016). WB . PubMed: 27259277
- Huot G et al. CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis. Mol Biol Cell 25:554-65 (2014). PubMed: 24403608