Overview
- Product nameAnti-CHRDL1 antibodySee all CHRDL1 primary antibodies ...
- DescriptionRabbit polyclonal to CHRDL1
- Tested applicationsWB more details
- Species reactivityReacts with: Mouse, Human
- Immunogen
Recombinant full length protein, corresponding to amino acids 1-450 of Human CHRDL1 (ENSP00000361115)
- Positive controlMouse kidney tissue lysate.
Properties
- FormLiquid
- Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Storage bufferPreservative: None
Constituents: PBS, pH 7.2 -
Concentration information loading... - PurityProtein A purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab103369 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/500 - 1/1000. Predicted molecular weight: 51 kDa. |
Target
- FunctionAntagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
- Tissue specificityExpressed in retinal pericytes.
- Sequence similaritiesContains 3 VWFC domains.
- Cellular localizationSecreted.
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Database links
- Entrez Gene: 91851 Human
- Entrez Gene: 91851 Human
- Entrez Gene: 91851 Human
- Entrez Gene: 83453 Mouse
- Omim: 300350 Human
- SwissProt: Q9BU40 Human
- SwissProt: Q9BU40 Human
- SwissProt: Q9BU40 Human
- SwissProt: Q920C1 Mouse
- Unigene: 496587 Human
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Target information above from: UniProt accession
Q9BU40
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- CHL antibodychordin like 1 antibodyChordin-like protein 1 antibody
- CHRDL1 antibodyCRDL1_HUMAN antibodydA141H5.1 antibodyneuralin 1 antibodyNeuralin-1 antibodyNeurogenesin-1 antibodyNRLN1 antibodyVentroptin antibodyVOPT antibody
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Anti-CHRDL1 antibody images
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Western blot - CHRDL1 antibody (ab103369)Anti-CHRDL1 antibody (ab103369) at 1/500 dilution + Mouse kidney tissue lysate
Predicted band size : 51 kDa -
Western blot - CHRDL1 antibody (ab103369)All lanes : Anti-CHRDL1 antibody (ab103369) at 1/500 dilution
Lane 1 : CHRDL1 transfected 293T cell lysate
Lane 2 : 293T non-transfected cell lysate
Predicted band size : 51 kDa
References for Anti-CHRDL1 antibody (ab103369)
ab103369 has not yet been referenced specifically in any publications.
