Anti-COX IV antibody [20E8C12] - Mitochondrial Loading Control (ab14744)

ab14744 has been referenced in 65 publications.

1. Ogawa K et al. Heterogeneous levels of oxidative phosphorylation enzymes in rat adrenal glands. Acta Histochem 113:24-31 (2011). PubMed: 19767061
2. Strub GM et al. Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration. FASEB J 25:600-12 (2011). PubMed: 20959514
3. Azarashvili T et al. Calcium-induced permeability transition in rat brain mitochondria is promoted by carbenoxolone through targeting connexin43. Am J Physiol Cell Physiol 300:C707-20 (2011). PubMed: 21148408
4. Leadsham JE & Gourlay CW cAMP/PKA signaling balances respiratory activity with mitochondria dependent apoptosis via transcriptional regulation. BMC Cell Biol 11:92 (2010). PubMed: 21108829
5. Escobar-Alvarez S et al. Inhibition of human peptide deformylase disrupts mitochondrial function. Mol Cell Biol 30:5099-109 (2010). PubMed: 20805355
6. Mayr JA et al. Mitochondrial ATP synthase deficiency due to a mutation in the ATP5E gene for the F1 epsilon subunit. Hum Mol Genet 19:3430-9 (2010). PubMed: 20566710
7. Ylikallio E et al. High mitochondrial DNA copy number has detrimental effects in mice. Hum Mol Genet 19:2695-705 (2010). PubMed: 20413656
8. Patel BP et al. Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS. PLoS One 5:e9386 (2010). PubMed: 20195368
9. Rasola A et al. Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition. Proc Natl Acad Sci U S A 107:726-31 (2010). PubMed: 20080742
10. Mracek T et al. Downregulation of zinc-{alpha}2-glycoprotein in adipose tissue and liver of obese ob/ob mice and by tumour necrosis factor-alpha in adipocytes. J Endocrinol 204:165-72 (2010). PubMed: 19934249
11. de Melo IS et al. NOA36/ZNF330 is a conserved cystein-rich protein with proapoptotic activity in human cells. Biochim Biophys Acta 1793:1876-85 (2009). PubMed: 19895853
12. Fowler SL et al. Tissue-specific cross-reactivity of connexin32 antibodies: problems and solutions unique to the central nervous system. Cell Commun Adhes 16:117-30 (2009). PubMed: 19845480
13. Vázquez-Iglesias L et al. Avian reovirus sigmaA localizes to the nucleolus and enters the nucleus by a nonclassical energy- and carrier-independent pathway. J Virol 83:10163-75 (2009). PubMed: 19640987
14. Rackham O et al. Pentatricopeptide repeat domain protein 1 lowers the levels of mitochondrial leucine tRNAs in cells. Nucleic Acids Res 37:5859-67 (2009). PubMed: 19651879
15. de Souza-Pinto NC et al. Novel DNA mismatch-repair activity involving YB-1 in human mitochondria. DNA Repair (Amst) 8:704-19 (2009). PubMed: 19272840
16. Shen H et al. Astaxanthin reduces ischemic brain injury in adult rats. FASEB J 23:1958-68 (2009). PubMed: 19218497
17. Amano T et al. Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes. J Neurooncol 92:357-71 (2009). PubMed: 19357962
18. Kadohara K et al. Caspase-8 mediates mitochondrial release of pro-apoptotic proteins in a manner independent of its proteolytic activity in apoptosis induced by the protein synthesis inhibitor acetoxycycloheximide in human leukemia Jurkat cells. J Biol Chem 284:5478-87 (2009). PubMed: 19112105
19. Stone SJ et al. The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. J Biol Chem 284:5352-61 (2009). PubMed: 19049983
20. Niizuma K et al. Potential role of PUMA in delayed death of hippocampal CA1 neurons after transient global cerebral ischemia. Stroke 40:618-25 (2009). PubMed: 19095966
21. Cambier S et al. At environmental doses, dietary methylmercury inhibits mitochondrial energy metabolism in skeletal muscles of the zebra fish (Danio rerio). Int J Biochem Cell Biol 41:791-9 (2009). PubMed: 18765295
22. Weisová P et al. Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. J Neurosci 29:2997-3008 (2009). PubMed: 19261894
23. Ogborn DI et al. Effects of creatine and exercise on skeletal muscle of FRG1-transgenic mice. Can J Neurol Sci 39:225-31 (2012). WB; Mouse. PubMed: 22343158
24. Houstek J et al. Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains. Physiol Genomics 44:487-94 (2012). WB; Rat. PubMed: 22414913
25. Liu F et al. Sex differences in the response to poly(ADP-ribose) polymerase-1 deletion and caspase inhibition after stroke. Stroke 42:1090-6 (2011). PubMed: 21311064
26. Laulier C et al. Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes. Cancer Res 71:3590-602 (2011). PubMed: 21444675
27. Chen Y et al. Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proc Natl Acad Sci U S A 107:9035-42 (2010). WB; Mouse. PubMed: 20418503
28. Kuzhandaivel A et al. Extensive glial apoptosis develops early after hypoxic-dysmetabolic insult to the neonatal rat spinal cord in vitro. Neuroscience 169:325-38 (2010). WB; Rat. PubMed: 20466038
29. Oliva CR et al. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. J Biol Chem 285:39759-67 (2010). WB; Human. PubMed: 20870728
30. Beirowski B et al. Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo. J Neurosci 29:653-68 (2009). PubMed: 19158292
31. Mou Z et al. The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10. J Biol Chem 284:13629-40 (2009). WB, ICC/IF; Mouse. PubMed: 19304657
32. Anderson DD & Stover PJ SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis. PLoS One 4:e5839 (2009). WB; Mouse. PubMed: 19513116
33. Lemarie A & Grimm S Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells. Mitochondrion 9:254-60 (2009). PubMed: 19332149
34. Ahmed KM et al. Cyclin D1 in low-dose radiation-induced adaptive resistance. Oncogene 27:6738-48 (2008). WB; Human. PubMed: 18695676
35. Champattanachai V et al. Glucosamine Protects Neonatal Cardiomyocytes from Ischemia-Reperfusion Injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2. Am J Physiol Cell Physiol : (2008). PubMed: 18367586
36. Nesic O et al. Aquaporin 1 - a novel player in spinal cord injury. J Neurochem 105:628-40 (2008). PubMed: 18248364
37. Dahm F et al. Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice. Br J Cancer 98:98-105 (2008). PubMed: 18026195
38. Van Laar VS et al. Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: implications for Parkinson disease. Neurobiol Dis 29:477-89 (2008). PubMed: 18226537
39. Pu JL et al. Cardiac sulfonylurea receptor short form-based channels confer a glibenclamide-insensitive KATP activity. J Mol Cell Cardiol 44:188-200 (2008). PubMed: 18001767
40. Hashimoto T et al. Evidence for the mitochondrial lactate oxidation complex in rat neurons: demonstration of an essential component of brain lactate shuttles. PLoS ONE 3:e2915 (2008). IHC-FoFr; Rat. PubMed: 18698340
41. Kolb G & Kristie TM Association of the cellular coactivator HCF-1 with the Golgi apparatus in sensory neurons. J Virol 82:9555-63 (2008). ICC/IF; Cow. PubMed: 18667495
42. Haque ME et al. Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc Natl Acad Sci U S A 105:1716-21 (2008). WB; Mouse. PubMed: 18218782
43. Watson PA et al. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol 293:H246-59 (2007). PubMed: 17337597
44. Fukuda R et al. HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 129:111-22 (2007). WB, IP; Human. PubMed: 17418790
45. Bivik C et al. Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes. Carcinogenesis 28:537-44 (2007). PubMed: 16950797
46. Capaldi RA et al. Immunological approaches to the characterization and diagnosis of mitochondrial disease. Mitochondrion 4:417-26 (2004). PubMed: 16120403
47. Kim TH et al. Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome C release. Mol Biol Cell 15:3061-72 (2004). PubMed: 15107464
48. Hanson BJ et al. Cytochrome c oxidase-deficient patients have distinct subunit assembly profiles. J Biol Chem 276:16296-301 (2001). PubMed: 11278850
49. Soane L et al. C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway. J Immunol 167:2305-11 (2001). PubMed: 11490019
50. Liu M & Spremulli L Interaction of mammalian mitochondrial ribosomes with the inner membrane. J Biol Chem 275:29400-6 (2000). PubMed: 10887179
51. Atlante A et al. Cytochrome c is released from mitochondria in a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic death. J Biol Chem 275:37159-66 (2000). PubMed: 10980192
52. Liu H et al. Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis. J Biol Chem 275:40155-62 (2000). PubMed: 11016920
53. Zhou H et al. Akt regulates cell survival and apoptosis at a postmitochondrial level. J Cell Biol 151:483-94 (2000). PubMed: 11062251
54. Clark RS et al. Caspase-3 mediated neuronal death after traumatic brain injury in rats. J Neurochem 74:740-53 (2000). PubMed: 10646526
55. Wagenknecht B et al. Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release. J Neurochem 75:2288-97 (2000). PubMed: 11080180
56. von Kleist-Retzow JC et al. Biochemical, genetic and immunoblot analyses of 17 patients with an isolated cytochrome c oxidase deficiency. Biochim Biophys Acta 1455:35-44 (1999). PubMed: 10524227
57. Wu Z et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98:115-24 (1999). PubMed: 10412986
58. Tang D et al. Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism. J Biol Chem 274:7245-52 (1999). PubMed: 10066786
59. Desagher S et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol 144:891-901 (1999). PubMed: 10085289
60. Luo X et al. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481-90 (1998). PubMed: 9727491
61. Vander Heiden MG et al. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91:627-37 (1997). PubMed: 9393856
62. Taanman JW et al. Molecular mechanisms in mitochondrial DNA depletion syndrome. Hum Mol Genet 6:935-42 (1997). PubMed: 9175742
63. Capaldi RA et al. Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells. Methods Enzymol 260:117-32 (1995). PubMed: 8592440
64. Taanman JW et al. Tissue distribution of cytochrome c oxidase isoforms in mammals. Characterization with monoclonal and polyclonal antibodies. Biochim Biophys Acta 1225:95-100 (1993). PubMed: 8241294
65. Capaldi RA et al. Complexity and tissue specificity of the mitochondrial respiratory chain. J Bioenerg Biomembr 20:291-311 (1988). PubMed: 2841307